[HTML][HTML] Eudragit®: A Versatile Family of Polymers for Hot Melt Extrusion and 3D Printing Processes in Pharmaceutics
J Dos Santos, GS da Silva, MC Velho, RCR Beck - Pharmaceutics, 2021 - mdpi.com
Eudragit® polymers are polymethacrylates highly used in pharmaceutics for the
development of modified drug delivery systems. They are widely known due to their …
development of modified drug delivery systems. They are widely known due to their …
Systematic screening of pharmaceutical polymers for hot melt extrusion processing: A comprehensive review
Pharmaceutical research, whether industrial or academic, has attempted to adopt
approaches most efficient for the development of innovations. With the abundance of …
approaches most efficient for the development of innovations. With the abundance of …
Role of release modifiers to modulate drug release from fused deposition modelling (FDM) 3D printed tablets
Although hot melt extrusion (HME) has been used in combination with fused deposition
modelling (FDM) three-dimensional printing (3DP), suitable feedstock materials such as …
modelling (FDM) three-dimensional printing (3DP), suitable feedstock materials such as …
[HTML][HTML] Hot-melt extrusion in the pharmaceutical industry: toward filing a new drug application
MF Simões, RMA Pinto, S Simões - Drug Discovery Today, 2019 - Elsevier
The pharmaceutical development of amorphous solid dispersions (ASDs) by hot-melt
extrusion (HME) is briefly reviewed. A systematic step-by-step approach is presented, where …
extrusion (HME) is briefly reviewed. A systematic step-by-step approach is presented, where …
Novel strategies for the formulation and processing of poorly water-soluble drugs
K Göke, T Lorenz, A Repanas, F Schneider… - European Journal of …, 2018 - Elsevier
Low aqueous solubility of active pharmaceutical ingredients presents a serious challenge in
the development process of new drug products. This article provides an overview on some …
the development process of new drug products. This article provides an overview on some …
Development of a hot-melt extrusion (HME) process to produce drug loaded Affinisol™ 15LV filaments for fused filament fabrication (FFF) 3D printing
The aim of the present work was to develop a pilot scale process to produce drug-loaded
filaments for 3D printing of oral solid dose forms by fused filament fabrication (FFF). Using …
filaments for 3D printing of oral solid dose forms by fused filament fabrication (FFF). Using …
Physical stability of amorphous solid dispersions: a physicochemical perspective with thermodynamic, kinetic and environmental aspects
X Lin, Y Hu, L Liu, L Su, N Li, J Yu, B Tang… - Pharmaceutical …, 2018 - Springer
Abstract Purpose Amorphous solid dispersions (ASDs) have been widely used in the
pharmaceutical industry for solubility enhancementof poorly water-soluble drugs. The …
pharmaceutical industry for solubility enhancementof poorly water-soluble drugs. The …
Molecular insight into drug-loading capacity of PEG–PLGA nanoparticles for itraconazole
N Wilkosz, G Łazarski, L Kovacik… - The Journal of …, 2018 - ACS Publications
Nanoparticles made of amphiphilic block copolymers comprising biodegradable core-
forming blocks are very attractive for the preparation of drug-delivery systems with sustained …
forming blocks are very attractive for the preparation of drug-delivery systems with sustained …
[HTML][HTML] Analytical and computational methods for the estimation of drug-polymer solubility and miscibility in solid dispersions development
The development of stable solid dispersion formulations that maintain desired improvement
of drug dissolution rate during the entire shelf life requires the analysis of drug-polymer …
of drug dissolution rate during the entire shelf life requires the analysis of drug-polymer …
Development of stability-enhanced ternary solid dispersions via combinations of HPMCP and Soluplus® processed by hot melt extrusion
The aim of this study was to evaluate a novel combination of hydroxypropyl methylcellulose
phthalate (HPMCP-HP-50) and Soluplus® polymers for enhanced physicochemical stability …
phthalate (HPMCP-HP-50) and Soluplus® polymers for enhanced physicochemical stability …