Prefrontal cortex and depression
DA Pizzagalli, AC Roberts - Neuropsychopharmacology, 2022 - nature.com
The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in
major depressive disorder (MDD). Although functional and structural PFC abnormalities …
major depressive disorder (MDD). Although functional and structural PFC abnormalities …
Altered connectivity in depression: GABA and glutamate neurotransmitter deficits and reversal by novel treatments
The mechanisms underlying the pathophysiology and treatment of depression and stress-
related disorders remain unclear, but studies in depressed patients and rodent models are …
related disorders remain unclear, but studies in depressed patients and rodent models are …
Resting-state fMRI functional connectivity and mindfulness in clinical and non-clinical contexts: A review and synthesis
This review synthesizes relations between mindfulness and resting-state fMRI functional
connectivity of brain networks. Mindfulness is characterized by present-moment awareness …
connectivity of brain networks. Mindfulness is characterized by present-moment awareness …
[HTML][HTML] Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms
RL Carhart-Harris, L Roseman, M Bolstridge… - Scientific reports, 2017 - nature.com
Psilocybin with psychological support is showing promise as a treatment model in psychiatry
but its therapeutic mechanisms are poorly understood. Here, cerebral blood flow (CBF) and …
but its therapeutic mechanisms are poorly understood. Here, cerebral blood flow (CBF) and …
Glutamate and gamma-aminobutyric acid systems in the pathophysiology of major depression and antidepressant response to ketamine
In patients with major depressive disorder or bipolar disorder, abnormalities in excitatory
and/or inhibitory neurotransmission and neuronal plasticity may lead to aberrant functional …
and/or inhibitory neurotransmission and neuronal plasticity may lead to aberrant functional …
Functional reorganization of the default mode network across chronic pain conditions
Chronic pain is associated with neuronal plasticity. Here we use resting-state functional
magnetic resonance imaging to investigate functional changes in patients suffering from …
magnetic resonance imaging to investigate functional changes in patients suffering from …
Depression, neuroimaging and connectomics: a selective overview
Depression is a multifactorial disorder with clinically heterogeneous features involving
disturbances of mood and cognitive function. Noninvasive neuroimaging studies have …
disturbances of mood and cognitive function. Noninvasive neuroimaging studies have …
Resting state brain network function in major depression–depression symptomatology, antidepressant treatment effects, future research
J Brakowski, S Spinelli, N Dörig, OG Bosch… - Journal of psychiatric …, 2017 - Elsevier
The alterations of functional connectivity brain networks in major depressive disorder (MDD)
have been subject of a large number of studies. Using different methodologies and focusing …
have been subject of a large number of studies. Using different methodologies and focusing …
Ketamine has distinct electrophysiological and behavioral effects in depressed and healthy subjects
Ketamine's mechanism of action was assessed using gamma power from
magnetoencephalography (MEG) as a proxy measure for homeostatic balance in 35 …
magnetoencephalography (MEG) as a proxy measure for homeostatic balance in 35 …
Ketamine treatment and global brain connectivity in major depression
Capitalizing on recent advances in resting-state functional connectivity magnetic resonance
imaging (rs-fcMRI) and the distinctive paradigm of rapid mood normalization following …
imaging (rs-fcMRI) and the distinctive paradigm of rapid mood normalization following …