Selenium: From fluorescent probes to biomedical application

J Wang, M Chen, Z Zhang, L Ma, T Chen - Coordination Chemistry Reviews, 2023 - Elsevier
Selenium (Se) is of fundamental importance to human health as an essential trace element,
mainly through regulation of selenoproteins (SePs). Therefore, monitoring Se transformation …

“Alphabet” selenoproteins: their characteristics and physiological roles

CB Dogaru, C Muscurel, C Duță, I Stoian - International Journal of …, 2023 - mdpi.com
Selenium (Se) is a metalloid that is recognized as one of the vital trace elements in our body
and plays multiple biological roles, largely mediated by proteins containing selenium …

[HTML][HTML] Selenoprotein S maintains intestinal homeostasis in ulcerative colitis by inhibiting necroptosis of colonic epithelial cells through modulation of macrophage …

Y Yao, T Xu, X Li, X Shi, H Wu, Z Zhang, S Xu - Theranostics, 2024 - ncbi.nlm.nih.gov
Rationale: Macrophage polarization plays an important role in the inflammatory regulation of
ulcerative colitis (UC). In this context, necroptosis is a type of cell death that regulates …

New-onset autoantibodies to selenoprotein P following severe burn injury

TL Turan, HJ Klein, TR Graf, TS Chillon… - Frontiers in …, 2024 - frontiersin.org
The liver-derived selenium (Se) transporter selenoprotein P (SELENOP) declines in critical
illness as a negative acute phase reactant and has recently been identified as an …

[HTML][HTML] Effect of Selenium and Selenoproteins on Radiation Resistance

S Zhang, G Zhang, P Wang, L Wang, B Fang, J Huang - Nutrients, 2024 - mdpi.com
With the advancement of radiological medicine and nuclear industry technology, radiation is
increasingly used to diagnose human health disorders. However, large-scale nuclear …

Selenoprotein S interacts with the replication and transcription complex of SARS-CoV-2 by binding nsp7

F Ghelichkhani, FA Gonzalez, MA Kapitonova… - Journal of Molecular …, 2023 - Elsevier
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) replicates and evades
detection using ER membranes and their associated protein machinery. Among these …

Selenoprotein S (SELENOS) is a potential prognostic biomarker for Brain lower grade glioma

Y Wang, K Qu, Z Xia, M Qi, X Du, Z Ke… - Journal of Trace Elements …, 2024 - Elsevier
Background Selenium, an essential micronutrient, primarily exists as selenocysteine in
various selenoproteins. Selenoprotein S (SELENOS) is crucial in the development of human …

Current understanding of essential trace elements in intrahepatic cholestasis of pregnancy

D Shan, Q Chen, Y Xie, S Dai, Y Hu - BioMetals, 2024 - Springer
Trace elements are important components in the body and have fundamental roles in
maintaining a healthy and balanced pregnancy process. Either deficiency or excess of trace …

Targeting BRF2: insights from in silico screening and molecular dynamic simulations

AS Rathore, KK Gupta, SK Govindaraj… - Journal of …, 2023 - Taylor & Francis
Abstract The Transcription factor II B (TFIIB)‑related factor 2 (BRF2) containing TFIIIB
complex recruits RNA polymerase III multi-subunit complex to selective gene promoters that …

Low expression of selenoprotein S induces oxidative damage in cartilages

Y Cui, Y Liao, Y Chen, X Zhao, Y Zhang… - Journal of Trace …, 2024 - Elsevier
Low levels of the indispensable trace element selenium (Se) can cause oxidative stress and
disrupt environmental homeostasis in humans and animals. Selenoprotein S (Selenos), of …