Singlet oxygen (1O2) is a biologically relevant reactive oxygen species capable of efficiently
reacting with cellular constituents. The resulting oxidatively generated damage to nucleic …

Nitric oxide (NO) is a key signalling molecule in the cardiovascular, immune and central
nervous systems, and crucial steps in the regulation of NO bioavailability in health and …

This article provides a succinct but limited overview of the protective and deleterious effects
of reactive oxygen and nitrogen species in a clinical context. Reactive oxygen species …

Nitric oxide (NO) and its derivatives play important roles in the physiology and
pathophysiology of the liver. Despite its diverse and complicated roles, certain patterns of …

The free radical nitric oxide (NO•) exerts biological effects through the direct and reversible
interaction with specific targets (eg soluble guanylate cyclase) or through the generation of …

Global epidemiological studies show that chronic non-communicable diseases such as
atherosclerosis and metabolic disorders represent the leading cause of premature mortality …

Airway oxidative stress is broadly defined as an imbalance between prooxidative and
antioxidative processes in the airway. Given its direct exposure to the environment, the lung …

Reactive nitrogen species (RNS) have gained a significant attention in recent years due to
their indispensable role in mechanisms regulating various biological processes of plant …

Oxylipins are lipid mediators produced from polyunsaturated fatty acid (PUFA) metabolism,
and are thought to be a molecular explanation for the diverse biological effects of PUFAs …

Polyphenols, members of phytochemical superfamily rich in vegetables and fruits, include
flavonoids, non-flavonoids, and phenolic acids. Their biological effects includes classical …