The two-pore-domain K+ channels, or K2P channels, constitute a novel class of K+ channel
subunits. They have four transmembrane segments and are active as dimers. The tissue …

The serum-and glucocorticoid-inducible kinase-1 (SGK1) is ubiquitously expressed and
under genomic control by cell stress (including cell shrinkage) and hormones (including …

K+ channels are widely distributed in both plant and animal cells where they serve many
distinct functions. K+ channels set the membrane potential, generate electrical signals in …

The margatoxin-sensitive Kv1. 3 is the major potassium channel in the plasma membrane of
T lymphocytes. Electron microscopy, patch clamp, and immunological studies identified the …

Kv1. 3 is a voltage-gated potassium (K) channel expressed in a number of tissues, including
fat and skeletal muscle. Channel inhibition improves experimental autoimmune encephalitis …

The field of mitochondrial ion channels underwent a rapid development during the last
decade, thanks to the molecular identification of some of the nuclear-encoded organelle …

Voltage-gated potassium (Kv) channels regulate cell membrane potential and control a
variety of cellular processes. Kv1. 3 channels are expressed in several tissues and believed …

Introduction: The voltage-dependent potassium channel Kv1. 3 is mainly present in the
nervous and immune systems. In leukocytes, Kv1. 3 fine-tunes the activation and …

The voltage-gated potassium channel KV 1.3 is a well-established therapeutic target for a
range of autoimmune diseases, in addition to being the site of action of many venom-derived …

Coronary blood flow is tightly adjusted to the oxygen requirements of the myocardium. The
underlying control mechanisms keep coronary venous pO2 at a rather constant level around …