High level extracellular production of recombinant human interferon alpha 2b in glycoengineered Pichia pastoris: culture medium optimization, high cell density …
Aims The present study was aimed at design of experiments (DoE)‐and artificial intelligence‐
based culture medium optimization for high level extracellular production of a novel …
based culture medium optimization for high level extracellular production of a novel …
Control of specific growth rate for the enhanced production of human interferon α2b in glycoengineered Pichia pastoris: process analytical technology guided …
BACKGROUND Process variability in bioprocess systems involving genetically engineered
strains is a common bottleneck and a real‐time insight of the on‐going process is crucial to …
strains is a common bottleneck and a real‐time insight of the on‐going process is crucial to …
[PDF][PDF] Antiproliferative activity of recombinant human interferon alpha2B on estrogen positive human breast cancer MCF-7 cell line
RA Ningrum, PH Wisnuwardhani… - Indonesian Journal …, 2015 - pdfs.semanticscholar.org
Indonesia is the top three countries with hepatitis and moreover has 40.000 cancer
mortalities per year. Interferon alpha 2b (IFNα-2b) is a therapeutic standard for cancer and …
mortalities per year. Interferon alpha 2b (IFNα-2b) is a therapeutic standard for cancer and …
[PDF][PDF] Expression of No Affinity Tagged Recombinant Human Interferon Alpha-2a in Methilotropic Yeast Pichia pastoris
Recombinant human interferon alpha-2a (rhIFNα-2a) has been widely used for clinical
therapy as antiviral, anticancer as well as immunomodulator. In this study, the open reading …
therapy as antiviral, anticancer as well as immunomodulator. In this study, the open reading …
[HTML][HTML] Removing a Cystein Group On Interferon Alpha 2b at Position 2 and 99 does Not Diminish Antitumor Activity of the Protein, Even Better
H Rachmawati, A Jessica… - Scientia …, 2016 - pmc.ncbi.nlm.nih.gov
Interferon alpha 2b is the only standard therapeutic protein for hepatitis virus infections.
Further study demonstrated that this protein also posseses antitumor activity in several …
Further study demonstrated that this protein also posseses antitumor activity in several …
Evaluation of Adverse Effects of Mutein Forms of Recombinant Human Interferon Alpha‐2b in Female Swiss Webster Mice
H Rachmawati, A Merika, RA Ningrum… - BioMed Research …, 2013 - Wiley Online Library
Purpose. We successfully developed recombinant human interferon alpha‐2b (rhIFN‐α2b)
and mutein forms through the site‐directed mutagenesis technique. The mutein forms were …
and mutein forms through the site‐directed mutagenesis technique. The mutein forms were …
[PDF][PDF] Research Article Evaluation of Adverse Effects of Mutein Forms of Recombinant Human Interferon Alpha-2b in Female Swiss Webster Mice
Purpose. We successfully developed recombinant human interferon alpha-2b (rhIFN- 2b)
and mutein forms through the sitedirected mutagenesis technique. he mutein forms were …
and mutein forms through the sitedirected mutagenesis technique. he mutein forms were …
[引用][C] Roferon-A: a biologic product of human interferon alpha 2a
A Wardiana, RA Ningrum - Annales Bogorienses-Journal of Tropical General …, 2015
[引用][C] Over Production of Human Recombinant Interferon a-2b: Scaling up Process
RA Susilo, YC Sumirtapura… - Journal of …, 2012 - Asian Network for Scientific …