[HTML][HTML] Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

T Zhao, W Wu, L Sui, Q Huang, Y Nan, J Liu, K Ai - Bioactive Materials, 2022 - Elsevier
Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial
infarction, but morbidity and mortality of acute myocardial infarction are still high …

Stimuli-responsive nanobubbles for biomedical applications

R Xiong, RX Xu, C Huang, S De Smedt… - Chemical Society …, 2021 - pubs.rsc.org
Stimuli-responsive nanobubbles have received increased attention for their application in
spatial and temporal resolution of diagnostic techniques and therapies, particularly in …

d-lactate modulates M2 tumor-associated macrophages and remodels immunosuppressive tumor microenvironment for hepatocellular carcinoma

S Han, X Bao, Y Zou, L Wang, Y Li, L Yang, A Liao… - Science …, 2023 - science.org
The polarization of tumor-associated macrophages (TAMs) from M2 to M1 phenotype
demonstrates great potential for remodeling the immunosuppressive tumor …

[HTML][HTML] Emerging non-viral vectors for gene delivery

C Wang, C Pan, H Yong, F Wang, T Bo, Y Zhao… - Journal of …, 2023 - Springer
Gene therapy holds great promise for treating a multitude of inherited and acquired diseases
by delivering functional genes, comprising DNA or RNA, into targeted cells or tissues to elicit …

[HTML][HTML] DNA vaccines—how far from clinical use?

D Hobernik, M Bros - International journal of molecular sciences, 2018 - mdpi.com
Two decades ago successful transfection of antigen presenting cells (APC) in vivo was
demonstrated which resulted in the induction of primary adaptive immune responses. Due to …

Degradable controlled-release polymers and polymeric nanoparticles: mechanisms of controlling drug release

N Kamaly, B Yameen, J Wu, OC Farokhzad - Chemical reviews, 2016 - ACS Publications
The development of biodegradable polymers represents a revolution in medicine spanning
over 50 years and leading to significant biotechnological advancements in drug delivery …

Gas-mediated cancer bioimaging and therapy

L Chen, SF Zhou, L Su, J Song - ACS nano, 2019 - ACS Publications
Gas-involving cancer theranostics have attracted considerable attention in recent years due
to their high therapeutic efficacy and biosafety. We have reviewed the recent significant …

Non-viral delivery systems for CRISPR/Cas9-based genome editing: Challenges and opportunities

L Li, S Hu, X Chen - Biomaterials, 2018 - Elsevier
In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas
(CRISPR-associated) genome editing systems have become one of the most robust …

Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics

D Ding, Q Zhu - Materials Science and Engineering: C, 2018 - Elsevier
Recent advancements in biopharmaceutical industry have facilitated the development of
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …

Nano co-delivery of Plumbagin and Dihydrotanshinone I reverses immunosuppressive TME of liver cancer

S Han, S Bi, T Guo, D Sun, Y Zou, L Wang… - Journal of Controlled …, 2022 - Elsevier
Hepatocellular carcinoma (HCC) is resistant to current immunotherapy. This poor outcome
mainly results from the immunosuppressive characteristics of tumor microenvironment …