[HTML][HTML] Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries
Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial
infarction, but morbidity and mortality of acute myocardial infarction are still high …
infarction, but morbidity and mortality of acute myocardial infarction are still high …
Stimuli-responsive nanobubbles for biomedical applications
Stimuli-responsive nanobubbles have received increased attention for their application in
spatial and temporal resolution of diagnostic techniques and therapies, particularly in …
spatial and temporal resolution of diagnostic techniques and therapies, particularly in …
d-lactate modulates M2 tumor-associated macrophages and remodels immunosuppressive tumor microenvironment for hepatocellular carcinoma
S Han, X Bao, Y Zou, L Wang, Y Li, L Yang, A Liao… - Science …, 2023 - science.org
The polarization of tumor-associated macrophages (TAMs) from M2 to M1 phenotype
demonstrates great potential for remodeling the immunosuppressive tumor …
demonstrates great potential for remodeling the immunosuppressive tumor …
[HTML][HTML] Emerging non-viral vectors for gene delivery
C Wang, C Pan, H Yong, F Wang, T Bo, Y Zhao… - Journal of …, 2023 - Springer
Gene therapy holds great promise for treating a multitude of inherited and acquired diseases
by delivering functional genes, comprising DNA or RNA, into targeted cells or tissues to elicit …
by delivering functional genes, comprising DNA or RNA, into targeted cells or tissues to elicit …
[HTML][HTML] DNA vaccines—how far from clinical use?
D Hobernik, M Bros - International journal of molecular sciences, 2018 - mdpi.com
Two decades ago successful transfection of antigen presenting cells (APC) in vivo was
demonstrated which resulted in the induction of primary adaptive immune responses. Due to …
demonstrated which resulted in the induction of primary adaptive immune responses. Due to …
Degradable controlled-release polymers and polymeric nanoparticles: mechanisms of controlling drug release
The development of biodegradable polymers represents a revolution in medicine spanning
over 50 years and leading to significant biotechnological advancements in drug delivery …
over 50 years and leading to significant biotechnological advancements in drug delivery …
Gas-mediated cancer bioimaging and therapy
Gas-involving cancer theranostics have attracted considerable attention in recent years due
to their high therapeutic efficacy and biosafety. We have reviewed the recent significant …
to their high therapeutic efficacy and biosafety. We have reviewed the recent significant …
Non-viral delivery systems for CRISPR/Cas9-based genome editing: Challenges and opportunities
L Li, S Hu, X Chen - Biomaterials, 2018 - Elsevier
In recent years, CRISPR (clustered regularly interspaced short palindromic repeat)/Cas
(CRISPR-associated) genome editing systems have become one of the most robust …
(CRISPR-associated) genome editing systems have become one of the most robust …
Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics
D Ding, Q Zhu - Materials Science and Engineering: C, 2018 - Elsevier
Recent advancements in biopharmaceutical industry have facilitated the development of
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …
Nano co-delivery of Plumbagin and Dihydrotanshinone I reverses immunosuppressive TME of liver cancer
S Han, S Bi, T Guo, D Sun, Y Zou, L Wang… - Journal of Controlled …, 2022 - Elsevier
Hepatocellular carcinoma (HCC) is resistant to current immunotherapy. This poor outcome
mainly results from the immunosuppressive characteristics of tumor microenvironment …
mainly results from the immunosuppressive characteristics of tumor microenvironment …