Post-translational modifications of histones that influence nucleosome dynamics
GD Bowman, MG Poirier - Chemical reviews, 2014 - ACS Publications
Nucleosomes are efficient DNA-packaging units. The fundamental protein unit of the
nucleosome is the histone dimer, a simple α-helical domain possessing a highly basic …
nucleosome is the histone dimer, a simple α-helical domain possessing a highly basic …
Histone variants and epigenetics
S Henikoff, MM Smith - Cold Spring Harbor perspectives …, 2015 - cshperspectives.cshlp.org
Histones package and compact DNA by assembling into nucleosome core particles. Most
histones are synthesized at S phase for rapid deposition behind replication forks. In addition …
histones are synthesized at S phase for rapid deposition behind replication forks. In addition …
[HTML][HTML] Chromatin modifications and their function
T Kouzarides - Cell, 2007 - cell.com
The surface of nucleosomes is studded with a multiplicity of modifications. At least eight
different classes have been characterized to date and many different sites have been …
different classes have been characterized to date and many different sites have been …
[HTML][HTML] The role of chromatin during transcription
Chromatin structure imposes significant obstacles on all aspects of transcription that are
mediated by RNA polymerase II. The dynamics of chromatin structure are tightly regulated …
mediated by RNA polymerase II. The dynamics of chromatin structure are tightly regulated …
Histone variants—ancient wrap artists of the epigenome
PB Talbert, S Henikoff - Nature reviews Molecular cell biology, 2010 - nature.com
Histones wrap DNA to form nucleosome particles that compact eukaryotic genomes. Variant
histones have evolved crucial roles in chromosome segregation, transcriptional regulation …
histones have evolved crucial roles in chromosome segregation, transcriptional regulation …
Global regulation of H2A. Z localization by the INO80 chromatin-remodeling enzyme is essential for genome integrity
M Papamichos-Chronakis, S Watanabe, OJ Rando… - Cell, 2011 - cell.com
INO80 is an evolutionarily conserved, ATP-dependent chromatin-remodeling enzyme that
plays roles in transcription, DNA repair, and replication. Here, we show that yeast INO80 …
plays roles in transcription, DNA repair, and replication. Here, we show that yeast INO80 …
Deposition of histone variant H2A. Z within gene bodies regulates responsive genes
D Coleman-Derr, D Zilberman - 2012 - journals.plos.org
The regulation of eukaryotic chromatin relies on interactions between many epigenetic
factors, including histone modifications, DNA methylation, and the incorporation of histone …
factors, including histone modifications, DNA methylation, and the incorporation of histone …
Histone H2A. Z controls a critical chromatin remodeling step required for DNA double-strand break repair
Y Xu, MK Ayrapetov, C Xu, O Gursoy-Yuzugullu, Y Hu… - Molecular cell, 2012 - cell.com
Chromatin remodeling during DNA double-strand break (DSB) repair is required to facilitate
access to and repair of DSBs. This remodeling requires increased acetylation of histones …
access to and repair of DSBs. This remodeling requires increased acetylation of histones …
Histone H2A. Z and DNA methylation are mutually antagonistic chromatin marks
Eukaryotic chromatin is separated into functional domains differentiated by post-translational
histone modifications, histone variants and DNA methylation,,,,,. Methylation is associated …
histone modifications, histone variants and DNA methylation,,,,,. Methylation is associated …