Inflammation is an important environmental factor that promotes tumourigenesis and the
progression of established cancerous lesions, and recent studies have started to dissect the …

Regenerating gene (Reg or REG) family, within the superfamily of C-type lectin, is mainly
involved in the liver, pancreatic, gastric and intestinal cell proliferation or differentiation …

Although gastrointestinal cancers are frequently associated with chronic inflammation, the
underlying molecular links have not been comprehensively deciphered. Using loss-and gain …

Human Reg and Reg-related genes constitute a multi-gene family belonging to the calcium
(C-type) dependent lectin superfamily. Regenerating gene family members are expressed in …

Activation of the nuclear hormone peroxisome proliferator-activated receptor γ (PPARγ)
inhibits cell growth and promotes differentiation in a broad spectrum of epithelial derived …

Background: This study examined the role of Survivin protein, a novel inhibitor of apoptosis,
in determining prognosis after curative resection of stage II colorectal carcinomas. Methods …

The regenerating (Reg) protein family comprises C-type lectin-like proteins discovered
independently during pancreatitis and pancreatic islet regeneration. However, an increasing …

Background & Aims: Reg IV, a secreted protein and member of the Reg multigene family, is
up-regulated in malignancies of the human gastrointestinal tract, including colorectal …

A better understanding of the mechanisms by which colon tumor cells are able to survive
exposure to drugs would be valuable for the development of new therapeutic strategies. We …

Regenerating gene (REG) family proteins serve as multifunctional secretory molecules with
trophic, antiapoptotic, anti-inflammatory, antimicrobial and probably immuno-regulatory …