Recent advances in the application of parahydrogen in catalysis and biochemistry

G Buntkowsky, F Theiss, J Lins, YA Miloslavina… - RSC …, 2022 - pubs.rsc.org
Nuclear Magnetic Resonance (NMR) spectroscopy and Magnetic Resonance Imaging (MRI)
are analytical and diagnostic tools that are essential for a very broad field of applications …

SABRE: Chemical kinetics and spin dynamics of the formation of hyperpolarization

DA Barskiy, S Knecht, AV Yurkovskaya… - Progress in Nuclear …, 2019 - Elsevier
In this review, we present the physical principles of the SABRE (Signal Amplification By
Reversible Exchange) method. SABRE is a promising hyperpolarization technique that …

In Situ Hyperpolarization Enables 15N and 13C Benchtop NMR at Natural Isotopic Abundance

R Kircher, J Xu, DA Barskiy - Journal of the American Chemical …, 2023 - ACS Publications
Without employing isotopic labeling, we demonstrate the generation of 15N and 13C NMR
signals for molecules containing− NH2 motifs using benchtop NMR spectrometers (1–1.4 T) …

SABRE-Relay: a versatile route to hyperpolarization

SS Roy, KM Appleby, EJ Fear… - The journal of physical …, 2018 - ACS Publications
Signal Amplification by Reversible Exchange (SABRE) is used to switch on the latent singlet
spin order of para-hydrogen (p-H2) so that it can hyperpolarize a substrate (sub …

Parahydrogen-based NMR signal amplification by reversible exchange (SABRE): Recent advances and applications

OG Salnikov, DB Burueva, IV Skovpin… - Mendeleev …, 2023 - Elsevier
Signal amplification by reversible exchange (SABRE) is a rapidly developing nuclear
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …

Direct and indirect hyperpolarisation of amines using para hydrogen

W Iali, PJ Rayner, A Alshehri, AJ Holmes… - Chemical …, 2018 - pubs.rsc.org
Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) are two
widely used techniques for the study of molecules and materials. Hyperpolarisation …

Reaction monitoring using SABRE-hyperpolarized benchtop (1 T) NMR spectroscopy

O Semenova, PM Richardson, AJ Parrott… - Analytical …, 2019 - ACS Publications
The conversion of [IrCl (COD)(IMes)](COD= cis, cis-1, 5-cyclooctadiene, IMes= 1, 3-bis (2, 4,
6-trimethyl-phenyl) imidazole-2-ylidene) in the presence of an excess of para-hydrogen (p …

Live magnetic observation of parahydrogen hyperpolarization dynamics

J Eills, MW Mitchell, IM Rius, MCD Tayler - Proceedings of the National …, 2024 - pnas.org
Hyperpolarized nuclear spins in molecules exhibit high magnetization that is unachievable
by classical polarization techniques, making them widely used as sensors in physics …

Water-Compatible and Recyclable Heterogeneous SABRE Catalyst for NMR Signal Amplification

S Min, J Baek, J Kim, HJ Jeong, J Chung, K Jeong - JACS Au, 2023 - ACS Publications
A water-compatible and recyclable catalyst for nuclear magnetic resonance (NMR)
hyperpolarization via signal amplification by reversible exchange (SABRE) was developed …

J Coupling Constants of <1 Hz Enable 13C Hyperpolarization of Pyruvate via Reversible Exchange of Parahydrogen

CD Assaf, X Gui, AA Auer, SB Duckett… - The Journal of …, 2024 - ACS Publications
Observing pyruvate metabolism in vivo has become a focal point of molecular magnetic
resonance imaging. Signal amplification by reversible exchange (SABRE) has recently …