Emergence of deep learning in knee osteoarthritis diagnosis

PSQ Yeoh, KW Lai, SL Goh, K Hasikin… - Computational …, 2021 - Wiley Online Library
Osteoarthritis (OA), especially knee OA, is the most common form of arthritis, causing
significant disability in patients worldwide. Manual diagnosis, segmentation, and …

[HTML][HTML] Osteoarthritis phenotypes and novel therapeutic targets

WE Van Spil, O Kubassova, M Boesen… - Biochemical …, 2019 - Elsevier
The success of disease-modifying osteoarthritis drug (DMOAD) development is still elusive.
While there have been successes in preclinical and early clinical studies, phase 3 clinical …

Concept bottleneck models

PW Koh, T Nguyen, YS Tang… - International …, 2020 - proceedings.mlr.press
We seek to learn models that we can interact with using high-level concepts: if the model did
not think there was a bone spur in the x-ray, would it still predict severe arthritis? State-of-the …

An algorithmic approach to reducing unexplained pain disparities in underserved populations

E Pierson, DM Cutler, J Leskovec, S Mullainathan… - Nature Medicine, 2021 - nature.com
Underserved populations experience higher levels of pain. These disparities persist even
after controlling for the objective severity of diseases like osteoarthritis, as graded by human …

Automatic instrument segmentation in robot-assisted surgery using deep learning

AA Shvets, A Rakhlin, AA Kalinin… - 2018 17th IEEE …, 2018 - ieeexplore.ieee.org
Semantic segmentation of robotic instruments is an important problem for the robot-assisted
surgery. One of the main challenges is to correctly detect an instrument's position for the …

Deep convolutional neural networks for breast cancer histology image analysis

A Rakhlin, A Shvets, V Iglovikov, AA Kalinin - Image Analysis and …, 2018 - Springer
Breast cancer is one of the main causes of cancer death worldwide. Early diagnostics
significantly increases the chances of correct treatment and survival, but this process is …

Deep learning for optic disc segmentation and glaucoma diagnosis on retinal images

S Sreng, N Maneerat, K Hamamoto, KY Win - Applied Sciences, 2020 - mdpi.com
Glaucoma is a major global cause of blindness. As the symptoms of glaucoma appear, when
the disease reaches an advanced stage, proper screening of glaucoma in the early stages is …

Fully automatic knee osteoarthritis severity grading using deep neural networks with a novel ordinal loss

P Chen, L Gao, X Shi, K Allen, L Yang - Computerized Medical Imaging and …, 2019 - Elsevier
Knee osteoarthritis (OA) is one major cause of activity limitation and physical disability in
older adults. Early detection and intervention can help slow down the OA degeneration …

Multimodal machine learning-based knee osteoarthritis progression prediction from plain radiographs and clinical data

A Tiulpin, S Klein, SMA Bierma-Zeinstra, J Thevenot… - Scientific reports, 2019 - nature.com
Knee osteoarthritis (OA) is the most common musculoskeletal disease without a cure, and
current treatment options are limited to symptomatic relief. Prediction of OA progression is a …

Automated skeletal classification with lateral cephalometry based on artificial intelligence

HJ Yu, SR Cho, MJ Kim, WH Kim… - Journal of dental …, 2020 - journals.sagepub.com
Lateral cephalometry has been widely used for skeletal classification in orthodontic
diagnosis and treatment planning. However, this conventional system, requiring manual …