The signaling component of the mammalian Fibroblast Growth Factor (FGF) family is
comprised of eighteen secreted proteins that interact with four signaling tyrosine kinase FGF …

Congenital diaphragmatic hernias (CDHs) and structural anomalies of the diaphragm are a
common class of congenital birth defects that are associated with significant morbidity and …

Congenital heart disease (CHD) affects nearly 1% of the population. It is a complex disease,
which may be caused by multiple genetic and environmental factors. Studies in human …

Since its discovery 40 years ago, fibroblast growth factor (FGF) receptor (FGFR) signalling
has been found to regulate fundamental cellular behaviours in a wide range of cell types …

Since 4p‐was first described in 1961, significant progress has been made in our
understanding of this classic deletion disorder. We have been able to establish a more …

The suite of adaptations associated with the extreme stature of the giraffe has long
interested biologists and physiologists. By generating a high-quality chromosome-level …

FGFRL1 (fibroblast growth factor receptor like 1) is the most recently discovered member of
the FGFR family. It contains three extracellular Ig-like domains similar to the classical …

Congenital diaphragmatic hernia (CDH) is a common birth defect that is associated with
significant morbidity and mortality, especially when associated with additional congenital …

The origins of giraffe's imposing stature and associated cardiovascular adaptations are
unknown. Okapi, which lacks these unique features, is giraffe's closest relative and provides …

The synchondroses formed via endochondral ossification in the cranial base are an
important growth center for the neurocranium. Abnormalities in the synchondroses affect …