[HTML][HTML] Neutrophil-Mediated Phagocytosis of Staphylococcus aureus

KPM van Kessel, J Bestebroer… - Frontiers in …, 2014 - frontiersin.org
Initial elimination of invading Staphylococcus aureus from the body is mediated by
professional phagocytes. The neutrophil is the major phagocyte of the innate immunity and …

Image‐based systems biology of infection

A Medyukhina, S Timme, Z Mokhtari… - Cytometry Part …, 2015 - Wiley Online Library
The successful treatment of infectious diseases requires interdisciplinary studies of all
aspects of infection processes. The overarching combination of experimental research and …

[HTML][HTML] Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling

L Luo, AA Wall, JC Yeo, ND Condon… - Nature …, 2014 - nature.com
Abstract Toll-like receptor 4 (TLR4) is activated by bacterial lipopolysaccharide (LPS) to
mount innate immune responses. The TLR4-induced release of pro-and anti-inflammatory …

A near-infrared plasma membrane-specific AIE probe for fluorescence lifetime imaging of phagocytosis

MY Wu, JK Leung, C Kam, TY Chou, JL Wang… - Science China …, 2022 - Springer
Phagocytosis is a biological process that plays a key role in host defense and tissue
homeostasis. Efficient approaches for realtime imaging of phagocytosis are highly desired …

Anti-CD20 monoclonal antibody-dependent phagocytosis of chronic lymphocytic leukaemia cells by autologous macrophages

AK Church, KR VanDerMeid, NA Baig… - Clinical & …, 2016 - academic.oup.com
Unconjugated monoclonal antibodies (mAbs) are an important component of effective
combination therapies for chronic lymphocytic leukaemia (CLL). Antibody-dependent …

Distribution of mast cell subtypes in interstitial cystitis: implications for novel diagnostic and therapeutic strategies?

ST Malik, BR Birch, D Voegeli, M Fader… - Journal of Clinical …, 2018 - jcp.bmj.com
Aims To identify the presence and geographical distribution of mast cell (MC) subtypes: MC
T (tryptase positive–chymase negative) and MC TC (tryptase positive–chymase positive) in …

Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages

JC Yeo, AA Wall, L Luo, JL Stow - Molecular biology of the cell, 2015 - Am Soc Cell Biol
Membrane remodeling in the early stages of phagocytosis enables the engulfment of
particles or pathogens and receptor signaling to activate innate immune responses …

Sequential recruitment of Rab GTPases during early stages of phagocytosis

JC Yeo, AA Wall, L Luo, JL Stow - Cellular logistics, 2016 - Taylor & Francis
The phagocytosis and destruction of pathogens and dead cells by macrophages is important
for innate immunity and tissue maintenance. Multiple Rab family GTPases engage effector …

Microglial phagocytosis/cell health high‐content assay

ER Mason, DM Soni, S Chu - Current protocols, 2023 - Wiley Online Library
We report a microglial phagocytosis/cell health high‐content assay that has been used to
test small molecule chemical probes and support our drug discovery projects targeting …

γ-Oryzanol-Rich Black Rice Bran Extract Enhances the Innate Immune Response

SY Shin, HW Kim, HH Jang, YJ Hwang… - Journal of medicinal …, 2017 - liebertpub.com
The innate immune response is an important host primary defense system against
pathogens. γ-Oryzanol is one of the nutritionally important phytoceutical components in rice …