Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …

Cannabis has a long history of anecdotal medicinal use and limited licensed medicinal use.
Until recently, alleged clinical effects from anecdotal reports and the use of licensed …

Learning to associate cues or contexts with potential threats or rewards is adaptive and
enhances survival. Both aversive and appetitive memories are therefore powerful drivers of …

A variety of classic psychedelics and MDMA have been shown to enhance fear extinction in
rodent models. This has translational significance because a standard treatment for post …

Although the cardinal manifestations of Parkinson's disease (PD) are attributed to a decline
in dopamine levels in the striatum, a breadth of non-motor features and treatment-related …

Summary Serotonin (5‐hydroxytryptamine or 5‐HT) is an important neurotransmitter
regulating a wide range of physiological and pathological functions via activation of …

Experimental evidence indicates that cannabidiol (CBD) induces anxiolytic and antiepileptic
effects through the activation of 5-HT1A receptors. These receptors are coupled to Gi/o …

Dopamine is an important neurotransmitter that regulates several key functions in the brain,
such as motor output, motivation and reward, learning and memory, and endocrine …

The serotonergic system plays a key modulatory role in the brain and is the target for many
drug treatments for brain disorders either through reuptake blockade or via interactions at …

Serotonin is an ancient monoamine neurotransmitter, biochemically derived from
tryptophan. It is most abundant in the gastrointestinal tract, but is also present throughout the …