Mycobacterium leprae, the causative agent of leprosy, is still actively transmitted in endemic
areas reflected by the fairly stable number of new cases detected each year. Recognizing …

Leprosy, which has afflicted human populations for millenia, results from infection with
Mycobacterium leprae, an unculturable pathogen with an exceptionally long generation …

Leprosy, caused by noncultivable Mycobacterium leprae (ML), has varied manifestations,
which are associated with the host immune responses. The dermal involvement is …

PGL-I (phenolic glycolipid I) emerged in the early 1980s on the one hand as part of intensive
efforts to define the typing antigens of a host of Mycobacterium spp. and also from …

Leprosy is not eradicable with currently available diagnostics or interventions, as evidenced
by its stable incidence. Early diagnosis of Mycobacterium leprae infection should therefore …

ABSTRACT A simple serodiagnostic test based on the Mycobacterium leprae-specific
phenolic glycolipid I (PGL-I), for individuals with leprosy is nearly universally positive in …

Background Leprosy is a chronic infectious disease caused by Mycobacterium leprae that
can manifest a wide variety of immunological and clinical outcomes ranging from potent …

Leprosy is a neglected chronic infectious disease caused by obligate intracellular bacilli,
Mycobacterium leprae and Mycobacterium lepromatosis. Despite multidrug therapy (MDT) …

This systematic review (number register: CRD42018112736) was performed to compare the
sensitivity and specificity of leprosy diagnostic methods. The search was conducted in 3 …

Background Although the number of newly detected leprosy cases has decreased globally,
a quarter of a million new cases are detected annually and eradication remains far away …