Oxytocin, neural plasticity, and social behavior

RC Froemke, LJ Young - Annual Review of Neuroscience, 2021 - annualreviews.org
Oxytocin regulates parturition, lactation, parental nurturing, and many other social behaviors
in both sexes. The circuit mechanisms by which oxytocin modulates social behavior are …

The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities

N Rigney, GJ de Vries, A Petrulis, LJ Young - Endocrinology, 2022 - academic.oup.com
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …

The transition to motherhood: linking hormones, brain and behaviour

C Servin-Barthet, M Martínez-García, C Pretus… - Nature Reviews …, 2023 - nature.com
We are witnessing a stark increase in scientific interest in the neurobiological processes
associated with pregnancy and maternity. Convergent evidence suggests that around the …

[HTML][HTML] Oxytocin in the anterior cingulate cortex attenuates neuropathic pain and emotional anxiety by inhibiting presynaptic long-term potentiation

XH Li, T Matsuura, M Xue, QY Chen, RH Liu, JS Lu… - Cell reports, 2021 - cell.com
Oxytocin is a well-known neurohypophysial hormone that plays an important role in
behavioral anxiety and nociception. Two major forms of long-term potentiation, presynaptic …

Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents

J Wahis, A Baudon, F Althammer, D Kerspern… - Nature …, 2021 - nature.com
Oxytocin (OT) orchestrates social and emotional behaviors through modulation of neural
circuits. In the central amygdala, the release of OT modulates inhibitory circuits and, thereby …

[HTML][HTML] Brain oxytocin: how puzzle stones from animal studies translate into psychiatry

V Grinevich, ID Neumann - Molecular psychiatry, 2021 - nature.com
The neuropeptide oxytocin has attracted great attention of the general public, basic
neuroscience researchers, psychologists, and psychiatrists due to its profound pro-social …

[HTML][HTML] Hippocampal oxytocin receptors are necessary for discrimination of social stimuli

T Raam, KM McAvoy, A Besnard, AH Veenema… - Nature …, 2017 - nature.com
Oxytocin receptor (Oxtr) signaling in neural circuits mediating discrimination of social stimuli
and affiliation or avoidance behavior is thought to guide social recognition. Remarkably, the …

[HTML][HTML] Biased oxytocinergic modulation of midbrain dopamine systems

L Xiao, MF Priest, J Nasenbeny, T Lu, Y Kozorovitskiy - Neuron, 2017 - cell.com
The release of dopamine (DA) regulates rewarding behavior and motor actions through
striatum-targeting efferents from ventral tegmental area (VTA) and substantia nigra pars …

Insular cortex mediates approach and avoidance responses to social affective stimuli

MM Rogers-Carter, JA Varela, KB Gribbons… - Nature …, 2018 - nature.com
Social animals detect the affective states of conspecifics and utilize this information to
orchestrate social interactions. In a social affective preference text in which experimental …