[HTML][HTML] Towards better antivenoms: navigating the road to new types of snakebite envenoming therapies

S Thumtecho, NJ Burlet, A Ljungars… - Journal of Venomous …, 2023 - SciELO Brasil
Snakebite envenoming is a significant global health challenge, and for over a century,
traditional plasma-derived antivenoms from hyperimmunized animals have been the primary …

Machine-learning guided venom induced dermonecrosis analysis tooL: VIDAL

W Laprade, KE Bartlett, CR Christensen… - Scientific Reports, 2023 - nature.com
Snakebite envenoming is a global public health issue that causes significant morbidity and
mortality, particularly in low-income regions of the world. The clinical manifestations of …

Investigating Snake-Venom-Induced Dermonecrosis and Inflammation Using an Ex Vivo Human Skin Model

J Alsolaiss, G Leeming, R Da Silva, N Alomran… - Toxins, 2024 - mdpi.com
Snakebite envenoming is a neglected tropical disease that causes> 100,000 deaths and>
400,000 cases of morbidity annually. Despite the use of mouse models, severe local …

[HTML][HTML] Global parameter optimisation and sensitivity analysis of antivenom pharmacokinetics and pharmacodynamics

NM Morris, JA Blee, S Hauert - Toxicon, 2023 - Elsevier
In recent years it has become possible to design snakebite antivenoms with diverse
pharmacokinetic properties. Owing to the pharmacokinetic variability of venoms, the choice …

Discerning Specific Thrombolytic Activities and Blood Clot Degradomes of Diverse Snake Venoms with Untargeted Peptidomics

CF Smith, M Alpha Balde, L Bahrabadi… - bioRxiv, 2024 - biorxiv.org
Identification and characterization of snake venom toxins that interfere with hemostasis have
important implications for the treatment of snake envenomation, the bioprospecting of …

[PDF][PDF] downloaded from Explore Bristol Research, http://research-information. bristol. ac. uk

P Agarwal - 2021 - research-information.bris.ac.uk
Working with a simplistic notion of release from bondage as “freedom”, mainstream anti-
trafficking activists focus on rescue. They argue that victims of trafficking are “free” once …