Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology

C Domingues, A Santos, C Alvarez-Lorenzo… - ACS …, 2022 - ACS Publications
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis

MC Bruno, MC Cristiano, C Celia, N d'Avanzo… - ACS …, 2022 - ACS Publications
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …

Advanced strategies to evade the mononuclear phagocyte system clearance of nanomaterials

J Lu, X Gao, S Wang, Y He, X Ma, T Zhang, X Liu - Exploration, 2023 - Wiley Online Library
Nanomaterials are promising carriers to improve the bioavailability and therapeutic
efficiency of drugs by providing preferential drug accumulation at their sites of action, but …

Multimodal smart systems reprogramme macrophages and remove urate to treat gouty arthritis

J Xu, M Wu, J Yang, D Zhao, D He, Y Liu, X Yan… - Nature …, 2024 - nature.com
Gouty arthritis is a chronic and progressive disease characterized by high urate levels in the
joints and by an inflammatory immune microenvironment. Clinical data indicate that urate …

DNA origami as a nanomedicine for targeted rheumatoid arthritis therapy through reactive oxygen species and nitric oxide scavenging

Y Ma, Z Lu, B Jia, Y Shi, J Dong, S Jiang, Z Li - ACS nano, 2022 - ACS Publications
Rheumatoid arthritis (RA) severely threatens human health by causing inflammation,
swelling, and pain in the joints and resulting in persistent synovitis and irreversible joint …

Multifunctional nanoparticles of sinomenine hydrochloride for treat-to-target therapy of rheumatoid arthritis via modulation of proinflammatory cytokines

Y Lin, O Yi, M Hu, S Hu, Z Su, J Liao, W Wang… - Journal of Controlled …, 2022 - Elsevier
Sinomenine is a bioactive alkaloid isolated from the Chinese medicinal plant of Sinomenium
acutum (Thunb.) Rehd. et Wils. Currently, sinomenine hydrochloride (SIN) preparations …

Biomarker‐responsive nanosystems for chronic disease theranostics

Q Fu, L Yu, Y Wang, P Li, J Song - Advanced Functional …, 2023 - Wiley Online Library
Chronic diseases claim millions of lives every year, and it is of great significance to explore
and develop advanced drugs to improve the cure rate of chronic diseases. Nanotheranostics …

Neutrophil‐Mimetic, ROS Responsive, and Oxygen Generating Nanovesicles for Targeted Interventions of Refractory Rheumatoid Arthritis

Z Tang, S Meng, X Yang, Y Xiao, W Wang, Y Liu, K Wu… - Small, 2024 - Wiley Online Library
Rheumatoid arthritis (RA) is the most prevalent inflammatory joint disease worldwide,
leading to irreversible disability and even mortality. Unfortunately, current treatment …

Advances in cell membrane-coated nanoparticles and their applications for bone therapy

Y Chen, M Zhu, B Huang, Y Jiang, J Su - Biomaterials Advances, 2023 - Elsevier
Due to the specific structure of natural bone, most of the therapeutics are incapable to be
delivered into the targeted site with effective concentrations. Nanotechnology has provided a …

Red blood cells: a potential delivery system

M Chen, Y Leng, C He, X Li, L Zhao, Y Qu… - Journal of …, 2023 - Springer
Red blood cells (RBCs) are the most abundant cells in the body, possessing unique
biological and physical properties. RBCs have demonstrated outstanding potential as …