Anaphylaxis is a severe systemic hypersensitivity reaction that is rapid in onset;
characterized by life-threatening airway, breathing, and/or circulatory problems; and usually …

Mast Cells, Mastocytosis, and Related Disorders | New England Journal of Medicine Skip to main
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Background An elevated basal serum tryptase level is associated with severe systemic
anaphylaxis, most notably caused by Hymenoptera envenomation. Although clonal mast cell …

Irrespective of the cause of cardiac arrest, early recognition and calling for help, including
appropriate management of the deteriorating patient, early defibrillation, high-quality …

This is the fourth iteration of this parameter entitled “The Diagnosis and Management of
Anaphylaxis.” The first anaphylaxis parameter was published in 1998 and the last in 2010 …

Mastocytosis is a hematopoietic neoplasm characterized by expansion of KIT D816V-
mutated clonal mast cells in various organs and severe or even life-threatening anaphylactic …

Elevated basal serum tryptase levels are present in 4–6% of the general population, but the
cause and relevance of such increases are unknown,. Previously, we described subjects …

Mast cell activation (MCA) accompanies diverse physiologic and pathologic processes and
is one of the more frequently encountered conditions in medicine. MCA-related symptoms …

Food allergy is an important public health problem that affects children and adults and may
be increasing in prevalence. Despite the risk of severe allergic reactions and even death …

Abstract The illustrated World Allergy Organization (WAO) Anaphylaxis Guidelines were
created in response to absence of global guidelines for anaphylaxis. Uniquely, before they …