Archaic humans have contributed to large-scale variation in modern human T cell receptor genes
M Corcoran, M Chernyshev, M Mandolesi, S Narang… - Immunity, 2023 - cell.com
Human T cell receptors (TCRs) are critical for mediating immune responses to pathogens
and tumors and regulating self-antigen recognition. Yet, variations in the genes encoding …
and tumors and regulating self-antigen recognition. Yet, variations in the genes encoding …
Specific TCR V–J gene segment recombinations leading to the identification pan-V–J CDR3s associated with survival distinctions: diffuse large B-cell lymphoma
KJ Cios, TI Huda, RA Eakins, MM Mihyu… - Leukemia & …, 2022 - Taylor & Francis
In the diffuse large B-cell lymphoma (DLBCL) setting, we examined lymph node biopsy, T-
cell receptor features, and the DLBLC patient human leukocyte antigen (HLA) alleles, to …
cell receptor features, and the DLBLC patient human leukocyte antigen (HLA) alleles, to …
Characteristics of T-Cell Receptor Repertoire for Differential Response to Methotrexate Treatment for Rheumatoid Arthritis
T Zhao, Q Zhang, Q Wen, S Liu, Z Niu… - Immunological …, 2024 - Taylor & Francis
Background Methotrexate (MTX) serves as the initial treatment for rheumatoid arthritis (RA).
However, a substantial proportion of RA patients, estimated between 30% and 50%, do not …
However, a substantial proportion of RA patients, estimated between 30% and 50%, do not …
TCR gene segment usage and HLA alleles that are associated with cancer survival rates also represent racial disparities
G Angelakakis, KS Serraneau… - International Journal …, 2023 - Wiley Online Library
Understanding racial disparities in cancer outcomes continues to be a challenge, with likely
many factors at play, including socioeconomic factors and genetic polymorphisms impacting …
many factors at play, including socioeconomic factors and genetic polymorphisms impacting …
Determination of most frequent major histocompatibility complex alleles in Iranian population by immunoinformatic
F Hajighasemi, A Shirkavand - Journal of Basic and Clinical …, 2024 - jbcp.shahed.ac.ir
Background and Objective: Major histocompatibility complex (MHC) is the most polymorphic
genes in human genome encoding human leukocyte antigens (HLA) class I and class II …
genes in human genome encoding human leukocyte antigens (HLA) class I and class II …
Microbial community composition in subgingival plaques and heterogeneity of tumor tissue TCRβ CDR3 repertoire in patients with moderate-to-severe periodontitis …
J Huang, K Yang, L Gao, Q He, S Ge - Technology and Health Care - content.iospress.com
BACKGROUND: The human oral cavity contains over 700 types of bacteria that may protect
the body against colonization by exogenous pathogens and maintain relative homeostasis …
the body against colonization by exogenous pathogens and maintain relative homeostasis …
[图书][B] Genetic and Functional Analysis of the Adaptive Immune Response
M Mandolesi - 2023 - search.proquest.com
The cells of the adaptive immune system rely on somatic recombination of V, D and J genes
to obtain a vast range of specificities. T cells use four chains encoded by three genomic loci …
to obtain a vast range of specificities. T cells use four chains encoded by three genomic loci …
[引用][C] Defining human adaptive immune gene diversity
S Narang - 2024 - Inst för mikrobiologi, tumör-och …