Lupus nephritis: new progress in diagnosis and treatment

C Yu, P Li, X Dang, X Zhang, Y Mao, X Chen - Journal of autoimmunity, 2022 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic multifactorial autoimmune disease that
affects many organs, including the kidney. Lupus nephritis (LN) is a common manifestation …

[HTML][HTML] Clinical and immunological biomarkers for systemic lupus erythematosus

H Yu, Y Nagafuchi, K Fujio - Biomolecules, 2021 - mdpi.com
Systemic lupus erythematosus (SLE) is characterized by immune system dysfunction and is
clinically heterogeneous, exhibiting renal, dermatological, neuropsychiatric, and …

Pathogenic cellular and molecular mediators in lupus nephritis

C Mohan, T Zhang, C Putterman - Nature Reviews Nephrology, 2023 - nature.com
Kidney involvement in patients with systemic lupus erythematosus—lupus nephritis (LN)—is
one of the most important and common clinical manifestations of this disease and occurs in …

Urine proteomics and renal single‐cell transcriptomics implicate interleukin‐16 in lupus nephritis

A Fava, DA Rao, C Mohan, T Zhang… - Arthritis & …, 2022 - Wiley Online Library
Objective Current lupus nephritis (LN) treatments are effective in only 30% of patients,
emphasizing the need for novel therapeutic strategies. We undertook this study to develop …

[HTML][HTML] Lupus nephritis risk factors and biomarkers: An update

Y Renaudineau, W Brooks, J Belliere - International Journal of Molecular …, 2023 - mdpi.com
Lupus nephritis (LN) represents the most severe organ manifestation of systemic lupus
erythematosus (SLE) in terms of morbidity and mortality. To reduce these risks, tremendous …

[HTML][HTML] Current insights on biomarkers in lupus nephritis: a systematic review of the literature

L Palazzo, J Lindblom, C Mohan, I Parodis - Journal of Clinical Medicine, 2022 - mdpi.com
Lupus nephritis (LN) is a major cause of morbidity and mortality among patients with
systemic lupus erythematosus (SLE). However, promising emerging biomarkers pave the …

[HTML][HTML] Combined proteomics and single cell RNA-sequencing analysis to identify biomarkers of disease diagnosis and disease exacerbation for systemic lupus …

Y Li, C Ma, S Liao, S Qi, S Meng, W Cai, W Dai… - Frontiers in …, 2022 - frontiersin.org
Introduction Systemic lupus erythematosus (SLE) is a chronic autoimmune disease for which
there is no cure. Effective diagnosis and precise assessment of disease exacerbation …

[HTML][HTML] Understanding the role and adoption of artificial intelligence techniques in rheumatology research: an in-depth review of the literature

A Madrid-García, B Merino-Barbancho… - Seminars in Arthritis and …, 2023 - Elsevier
The major and upward trend in the number of published research related to rheumatic and
musculoskeletal diseases, in which artificial intelligence plays a key role, has exhibited the …

[HTML][HTML] Urine proteomic signatures of histological class, activity, chronicity, and treatment response in lupus nephritis

A Fava, J Buyon, L Magder, J Hodgin, A Rosenberg… - JCI insight, 2024 - ncbi.nlm.nih.gov
Lupus nephritis (LN) is a pathologically heterogenous autoimmune disease linked to end-
stage kidney disease and mortality. Better therapeutic strategies are needed as only 30 …

[HTML][HTML] Urinary exosome tsRNAs as novel markers for diagnosis and prediction of lupus nephritis

S Chen, X Zhang, K Meng, Y Sun, R Shu… - Frontiers in …, 2023 - frontiersin.org
Objective Lupus nephritis (LN) is one of the most severe organ manifestations of systemic
lupus erythematosus (SLE). Early identification of renal disease in SLE is important. Renal …