Genetics meets proteomics: perspectives for large population-based studies
Proteomic analysis of cells, tissues and body fluids has generated valuable insights into the
complex processes influencing human biology. Proteins represent intermediate phenotypes …
complex processes influencing human biology. Proteins represent intermediate phenotypes …
Adipokines: a treasure trove for the discovery of biomarkers for metabolic disorders
S Lehr, S Hartwig, H Sell - PROTEOMICS–Clinical Applications, 2012 - Wiley Online Library
Adipose tissue is a major endocrine organ, releasing signaling and mediator proteins,
termed adipokines, via which adipose tissue communicates with other organs. Expansion of …
termed adipokines, via which adipose tissue communicates with other organs. Expansion of …
The clinical plasma proteome: a survey of clinical assays for proteins in plasma and serum
NL Anderson - Clinical chemistry, 2010 - academic.oup.com
An analysis of all US Food and Drug Administration (FDA) approvals for protein-based
assays through 2008 reveals 109 unique protein targets in plasma or serum, as well as 62 …
assays through 2008 reveals 109 unique protein targets in plasma or serum, as well as 62 …
Urine in clinical proteomics
S Decramer, AG de Peredo, B Breuil, H Mischak… - Molecular & cellular …, 2008 - ASBMB
Urine has become one of the most attractive biofluids in clinical proteomics as it can be
obtained non-invasively in large quantities and is stable compared with other biofluids. The …
obtained non-invasively in large quantities and is stable compared with other biofluids. The …
Isotope-labeled protein standards: toward absolute quantitative proteomics
V Brun, A Dupuis, A Adrait, M Marcellin… - Molecular & Cellular …, 2007 - ASBMB
Diagnostic development and public health surveillance require technologies that provide
specific identification and absolute quantification of protein biomarkers. Beside …
specific identification and absolute quantification of protein biomarkers. Beside …
Methods for samples preparation in proteomic research
A Bodzon-Kulakowska, A Bierczynska-Krzysik… - … of Chromatography B, 2007 - Elsevier
Sample preparation is one of the most crucial processes in proteomics research. The results
of the experiment depend on the condition of the starting material. Therefore, the proper …
of the experiment depend on the condition of the starting material. Therefore, the proper …
The blood peptidome: a higher dimension of information content for cancer biomarker discovery
The low-molecular-weight range of the circulatory proteome is termed the'peptidome', and
could be a rich source of cancer-specific diagnostic information because it is a'recording'of …
could be a rich source of cancer-specific diagnostic information because it is a'recording'of …
Significance of surface charge and shell material of superparamagnetic iron oxide nanoparticle (SPION) based core/shell nanoparticles on the composition of the …
As nanoparticles (NPs) are increasingly used in many applications their safety and efficient
applications in nanomedicine have become concerns. Protein coronas on nanomaterials' …
applications in nanomedicine have become concerns. Protein coronas on nanomaterials' …
Body fluid proteomics for biomarker discovery: lessons from the past hold the key to success in the future
DM Good, V Thongboonkerd, J Novak… - Journal of proteome …, 2007 - ACS Publications
Sparked by the article from Lescuyer and colleagues in a recent issue, we aim here to
further encourage interest in and discussion of clinically relevant biomarker research. We …
further encourage interest in and discussion of clinically relevant biomarker research. We …
Nanoformulation properties, characterization, and behavior in complex biological matrices: Challenges and opportunities for brain-targeted drug delivery applications …
V Agrahari, PA Burnouf, T Burnouf… - Advanced Drug Delivery …, 2019 - Elsevier
Nanocarriers (synthetic/cell-based have attracted enormous interest for various therapeutic
indications, including neurodegenerative disorders. A broader understanding of the impact …
indications, including neurodegenerative disorders. A broader understanding of the impact …