Genetics meets proteomics: perspectives for large population-based studies

K Suhre, MI McCarthy, JM Schwenk - Nature Reviews Genetics, 2021 - nature.com
Proteomic analysis of cells, tissues and body fluids has generated valuable insights into the
complex processes influencing human biology. Proteins represent intermediate phenotypes …

Adipokines: a treasure trove for the discovery of biomarkers for metabolic disorders

S Lehr, S Hartwig, H Sell - PROTEOMICS–Clinical Applications, 2012 - Wiley Online Library
Adipose tissue is a major endocrine organ, releasing signaling and mediator proteins,
termed adipokines, via which adipose tissue communicates with other organs. Expansion of …

The clinical plasma proteome: a survey of clinical assays for proteins in plasma and serum

NL Anderson - Clinical chemistry, 2010 - academic.oup.com
An analysis of all US Food and Drug Administration (FDA) approvals for protein-based
assays through 2008 reveals 109 unique protein targets in plasma or serum, as well as 62 …

Urine in clinical proteomics

S Decramer, AG de Peredo, B Breuil, H Mischak… - Molecular & cellular …, 2008 - ASBMB
Urine has become one of the most attractive biofluids in clinical proteomics as it can be
obtained non-invasively in large quantities and is stable compared with other biofluids. The …

Isotope-labeled protein standards: toward absolute quantitative proteomics

V Brun, A Dupuis, A Adrait, M Marcellin… - Molecular & Cellular …, 2007 - ASBMB
Diagnostic development and public health surveillance require technologies that provide
specific identification and absolute quantification of protein biomarkers. Beside …

Methods for samples preparation in proteomic research

A Bodzon-Kulakowska, A Bierczynska-Krzysik… - … of Chromatography B, 2007 - Elsevier
Sample preparation is one of the most crucial processes in proteomics research. The results
of the experiment depend on the condition of the starting material. Therefore, the proper …

The blood peptidome: a higher dimension of information content for cancer biomarker discovery

EF Petricoin, C Belluco, RP Araujo, LA Liotta - Nature Reviews Cancer, 2006 - nature.com
The low-molecular-weight range of the circulatory proteome is termed the'peptidome', and
could be a rich source of cancer-specific diagnostic information because it is a'recording'of …

Significance of surface charge and shell material of superparamagnetic iron oxide nanoparticle (SPION) based core/shell nanoparticles on the composition of the …

U Sakulkhu, M Mahmoudi, L Maurizi, G Coullerez… - Biomaterials …, 2015 - pubs.rsc.org
As nanoparticles (NPs) are increasingly used in many applications their safety and efficient
applications in nanomedicine have become concerns. Protein coronas on nanomaterials' …

Body fluid proteomics for biomarker discovery: lessons from the past hold the key to success in the future

DM Good, V Thongboonkerd, J Novak… - Journal of proteome …, 2007 - ACS Publications
Sparked by the article from Lescuyer and colleagues in a recent issue, we aim here to
further encourage interest in and discussion of clinically relevant biomarker research. We …

Nanoformulation properties, characterization, and behavior in complex biological matrices: Challenges and opportunities for brain-targeted drug delivery applications …

V Agrahari, PA Burnouf, T Burnouf… - Advanced Drug Delivery …, 2019 - Elsevier
Nanocarriers (synthetic/cell-based have attracted enormous interest for various therapeutic
indications, including neurodegenerative disorders. A broader understanding of the impact …