Extracellular matrix-derived biomaterials in engineering cell function

H Xing, H Lee, L Luo, TR Kyriakides - Biotechnology advances, 2020 - Elsevier
Extracellular matrix (ECM) derived components are emerging sources for the engineering of
biomaterials that are capable of inducing desirable cell-specific responses. This review …

[HTML][HTML] ECM and ECM-like materials—Biomaterials for applications in regenerative medicine and cancer therapy

S Hinderer, SL Layland, K Schenke-Layland - Advanced drug delivery …, 2016 - Elsevier
Regenerative strategies such as stem cell-based therapies and tissue engineering
applications are being developed with the aim to replace, remodel, regenerate or support …

3D printing of personalized thick and perfusable cardiac patches and hearts

N Noor, A Shapira, R Edri, I Gal, L Wertheim… - Advanced …, 2019 - Wiley Online Library
Generation of thick vascularized tissues that fully match the patient still remains an unmet
challenge in cardiac tissue engineering. Here, a simple approach to 3D‐print thick …

Extracellular matrix hydrogel therapies: In vivo applications and development

MT Spang, KL Christman - Acta biomaterialia, 2018 - Elsevier
Decellularized extracellular matrix (ECM) has been widely used for tissue engineering
applications and is becoming increasingly versatile as it can take many forms, including …

Gold nanorod-incorporated gelatin-based conductive hydrogels for engineering cardiac tissue constructs

A Navaei, H Saini, W Christenson, RT Sullivan, R Ros… - Acta biomaterialia, 2016 - Elsevier
The development of advanced biomaterials is a crucial step to enhance the efficacy of tissue
engineering strategies for treatment of myocardial infarction. Specific characteristics of …

Applications of decellularized extracellular matrix in bone and cartilage tissue engineering

YS Kim, M Majid, AJ Melchiorri… - … & translational medicine, 2019 - Wiley Online Library
Regenerative therapies for bone and cartilage injuries are currently unable to replicate the
complex microenvironment of native tissue. There are many tissue engineering approaches …

Natural biomaterials for cardiac tissue engineering: a highly biocompatible solution

QA Majid, ATR Fricker, DA Gregory… - Frontiers in …, 2020 - frontiersin.org
Cardiovascular diseases (CVD) constitute a major fraction of the current major global
diseases and lead to about 30% of the deaths, ie, 17.9 million deaths per year. CVD include …

Decellularized extracellular matrix materials for cardiac repair and regeneration

D Bejleri, ME Davis - Advanced healthcare materials, 2019 - Wiley Online Library
Decellularized extracellular matrix (dECM) is a promising biomaterial for repairing
cardiovascular tissue, as dECM most effectively captures the complex array of proteins …

Biomanufacturing human tissues via organ building blocks

KJ Wolf, JD Weiss, SGM Uzel, MA Skylar-Scott… - Cell Stem Cell, 2022 - cell.com
The construction of human organs on demand remains a tantalizing vision to solve the
organ donor shortage. Yet, engineering tissues that recapitulate the cellular and …

Bioengineering approaches to treat the failing heart: from cell biology to 3D printing

M Yadid, H Oved, E Silberman, T Dvir - Nature Reviews Cardiology, 2022 - nature.com
Successfully engineering a functional, human, myocardial pump would represent a
therapeutic alternative for the millions of patients with end-stage heart disease and provide …