Mass spectrometry-based metabolomics in microbiome investigations

A Bauermeister, H Mannochio-Russo… - Nature Reviews …, 2022 - nature.com
Microbiotas are a malleable part of ecosystems, including the human ecosystem.
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …

Stool multi-omics for the study of host–microbe interactions in inflammatory bowel disease

C Sauceda, C Bayne, K Sudqi, A Gonzalez… - Gut …, 2022 - Taylor & Francis
ABSTRACT Inflammatory Bowel Disease (IBD) is a chronic immune-mediated inflammatory
disease of the gastrointestinal tract that is a growing public burden. Gut microbes and their …

Comprehensive meta-analysis of COVID-19 global metabolomics datasets

Z Pang, G Zhou, J Chong, J Xia - Metabolites, 2021 - mdpi.com
The novel coronavirus SARS-CoV-2 has spread across the world since 2019, causing a
global pandemic. The pathogenesis of the viral infection and the associated clinical …

Native mass spectrometry-based metabolomics identifies metal-binding compounds

AT Aron, D Petras, R Schmid, JM Gauglitz, I Büttel… - Nature …, 2022 - nature.com
Although metals are essential for the molecular machineries of life, systematic methods for
discovering metal–small molecule complexes from biological samples are limited. Here, we …

Effects of a ketogenic and low‐fat diet on the human metabolome, microbiome, and foodome in adults at risk for Alzheimer's disease

AH Dilmore, C Martino, BJ Neth, KA West… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION The ketogenic diet (KD) is an intriguing therapeutic candidate for
Alzheimer's disease (AD) given its protective effects against metabolic dysregulation and …

Microbial and nonvolatile chemical diversities of Chinese dark teas are differed by latitude and pile fermentation

YS Kong, HY Ren, R Liu, RR da Silva… - Journal of Agricultural …, 2022 - ACS Publications
Understanding the microbial and chemical diversities, as well as what affects these
diversities, is important for modern manufacturing of traditional fermented foods. In this work …

foodMASST a mass spectrometry search tool for foods and beverages

KA West, R Schmid, JM Gauglitz, M Wang… - npj Science of …, 2022 - nature.com
There is a growing interest in unraveling the chemical complexity of our diets. To help the
scientific community gain insight into the molecules present in foods and beverages that we …

Predicting Tandem Mass Spectra of Small Molecules Using Graph Embedding of Precursor-Product Ion Pair Graph

F Zheng, L You, X Zhao, X Lu, G Xu - Analytical Chemistry, 2024 - ACS Publications
Liquid chromatography–mass spectrometry (LC-MS)-based metabolomics identification
relies heavily on high-quality MS/MS data; MS/MS prediction is a good way to address this …

The molecular impact of life in an indoor environment

AA Aksenov, RA Salido, AV Melnik, C Brennan… - Science …, 2022 - science.org
The chemistry of indoor surfaces and the role of microbes in shaping and responding to that
chemistry are largely unexplored. We found that, over 1 month, people's presence and …

Repository scale classification and decomposition of tandem mass spectral data

M Mongia, H Mohimani - Scientific Reports, 2021 - nature.com
Various studies have shown associations between molecular features and phenotypes of
biological samples. These studies, however, focus on a single phenotype per study and are …