The recent increase in interest in the chemistry of azoles has been owing to their paramount
importance in several essential fields of research, such as pharmacology, medicine, biology …

Protocols for the stereodefined formation of α, α-disubstituted enolates of pseudoephedrine
amides are presented followed by the implementation of these in diastereoselective …

The highly enantioselective synthesis of 2-aryl-and 2-vinyl-piperidines has been
accomplished through a catalytic dynamic resolution (CDR) of N-Boc-2-lithiopiperidine. The …

The organolithium species derived from proton abstraction of N-Boc-piperidine with s-BuLi
and TMEDA can be transmetalated to the organozinc reagent, and this organometallic …

Copper salts have been screened for transmetalation and electrophilic quench of N-tert-
butoxycarbonyl-2-lithiopyrrolidine (N-Boc-2-lithiopyrrolidine) and N-Boc-2-lithiopiperidine …

Both the R and S enantiomers of the amphibian alkaloid noranabasamine were prepared
in> 30% overall yield with 80% ee and 86% ee, respectively. An enantioselective iridium …

The conjugate addition of an enantiopure lithium amide to a ζ-hydroxy-α, β-unsaturated
ester followed by a one-pot ring-closure/N-debenzylation protocol has been used in the …

We have succeeded in accomplishing the deracemization of (±)-2-acetoxydecyl and (±)-
acetoxy-6-benzyloxyhexyl tosylates, which have a long substituent, via an enzyme-mediated …

A multicomponent reaction (MCR) based on a cyclohydrocarbonylation (CHC) driven by
hydroformylation was set up toward the efficient diastereoselective preparation of …

(2H)‐isoxazolone is an important skeletal structure in medicinal and agricultural chemistry.
However, its synthetic methodology has limited substrate scope and requires …