[HTML][HTML] Carrier-free nanodrugs for safe and effective cancer treatment
S Karaosmanoglu, M Zhou, B Shi, X Zhang… - Journal of Controlled …, 2021 - Elsevier
Clinical applications of many anti-cancer drugs are restricted due to their hydrophobic
nature, requiring use of harmful organic solvents for administration, and poor selectivity and …
nature, requiring use of harmful organic solvents for administration, and poor selectivity and …
[HTML][HTML] Recent advancements of nanomedicine towards antiangiogenic therapy in cancer
A Mukherjee, VS Madamsetty, MK Paul… - International Journal of …, 2020 - mdpi.com
Angiogenesis is a process of generation of de-novo blood vessels from already existing
vasculature. It has a crucial role in different physiological process including wound healing …
vasculature. It has a crucial role in different physiological process including wound healing …
[HTML][HTML] Recent advances of nanotechnology-based tumor vessel-targeting strategies
D Zhu, Y Li, Z Zhang, Z Xue, Z Hua, X Luo… - Journal of …, 2021 - Springer
Tumor vessels can provide oxygen and nutrition for solid tumor tissue, create abnormal
tumor microenvironment (TME), and play a vital role in the development, immune escape …
tumor microenvironment (TME), and play a vital role in the development, immune escape …
[HTML][HTML] Autophagy as a potential therapy for malignant glioma
A Escamilla-Ramírez, RA Castillo-Rodríguez… - Pharmaceuticals, 2020 - mdpi.com
Glioma is the most frequent and aggressive type of brain neoplasm, being anaplastic
astrocytoma (AA) and glioblastoma multiforme (GBM), its most malignant forms. The survival …
astrocytoma (AA) and glioblastoma multiforme (GBM), its most malignant forms. The survival …
[HTML][HTML] Tyrosine kinase inhibitors for glioblastoma multiforme: challenges and opportunities for drug delivery
Glioblastoma multiforme (GBM) is an aggressive brain tumor with high mortality rates. Due to
its invasiveness, heterogeneity, and incomplete resection, the treatment is very challenging …
its invasiveness, heterogeneity, and incomplete resection, the treatment is very challenging …
[HTML][HTML] Apatinib potentiates irradiation effect via suppressing PI3K/AKT signaling pathway in hepatocellular carcinoma
Background Limited effective intervention for advanced hepatocellular carcinoma (HCC) is
available. This study aimed to investigate the potential clinical utility of apatinib, a highly …
available. This study aimed to investigate the potential clinical utility of apatinib, a highly …
Lipid shell lipid nanocapsules as smart generation lipid nanocarriers
Lipid nanocapsules (LNCs) are lipid-based nanocarriers that have found application as drug
delivery systems, in diagnostics, and theranostics. They are biocompatible and able to …
delivery systems, in diagnostics, and theranostics. They are biocompatible and able to …
Bi/Se-based nanotherapeutics sensitize CT image-guided stereotactic body radiotherapy through reprogramming the microenvironment of hepatocellular carcinoma
The particular characteristics of hypoxia, immune suppression in the tumor
microenvironment, and the lack of accurate imaging guidance lead to the limited effects of …
microenvironment, and the lack of accurate imaging guidance lead to the limited effects of …
[HTML][HTML] Lipid nanocapsules enhance the transdermal delivery of drugs regardless of their physico-chemical properties
A Kalvodová, J Zbytovská - International Journal of Pharmaceutics, 2022 - Elsevier
The transdermal application of actives offers numerous advantages over other conventional
routes. Namely, a stable level of drugs in the bloodstream and reduced side effects are the …
routes. Namely, a stable level of drugs in the bloodstream and reduced side effects are the …
[HTML][HTML] Nanomedicine of tyrosine kinase inhibitors
V Smidova, P Michalek, Z Goliasova, T Eckschlager… - Theranostics, 2021 - ncbi.nlm.nih.gov
Recent progress in nanomedicine and targeted therapy brings new breeze into the field of
therapeutic applications of tyrosine kinase inhibitors (TKIs). These drugs are known for many …
therapeutic applications of tyrosine kinase inhibitors (TKIs). These drugs are known for many …