Klebsiella species cause a wide range of diseases including pneumonia, urinary tract
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …

Klebsiella pneumoniae causes a wide range of infections, including pneumonias, urinary
tract infections, bacteremias, and liver abscesses. Historically, K. pneumoniae has caused …

The global emergence of multidrug-resistant Gram-negative bacteria is a growing threat to
antibiotic therapy. The chromosomally encoded drug efflux mechanisms that are ubiquitous …

Tetracyclines possess many properties considered ideal for antibiotic drugs, including
activity against Gram-positive and-negative pathogens, proven clinical safety, acceptable …

Transporters belonging to the chromosomally encoded resistance-nodulation-division
(RND) superfamily mediate multidrug resistance in Gram-negative bacteria. However, the …

Antimicrobial-resistant Klebsiella pneumoniae (Kp) has emerged as a major global public
health problem. While resistance can occur across a broad range of Kp clones, a small …

Pathogens that infect the gastrointestinal and respiratory tracts are subjected to intense
pressure due to the environmental conditions of the surroundings. This pressure has led to …

Multidrug-resistant Klebsiella pneumoniae producing the KPC carbapenemase have rapidly
spread throughout the world, causing severe healthcare-associated infections with limited …

Background OqxAB efflux pump has been found to mediate multidrug resistance (MDR) in
various bacteria over the past decades. The updates on the nature and epidemiology of …

Rresistance-nodulation-division (RND) efflux pumps in Gram-negative bacteria remove
multiple, structurally distinct classes of antimicrobials from inside bacterial cells therefore …