Beyond the limiting gap length: peripheral nerve regeneration through implantable nerve guidance conduits
Peripheral nerve damage results in the loss of sensorimotor and autonomic functions, which
is a significant burden to patients. Furthermore, nerve injuries greater than the limiting gap …
is a significant burden to patients. Furthermore, nerve injuries greater than the limiting gap …
The bumpy road to stem cell therapies: Rational design of surface topographies to dictate stem cell mechanotransduction and fate
J Carthew, JBJ Taylor, MR Garcia-Cruz… - … Applied Materials & …, 2022 - ACS Publications
Cells sense and respond to a variety of physical cues from their surrounding
microenvironment, and these are interpreted through mechanotransductive processes to …
microenvironment, and these are interpreted through mechanotransductive processes to …
Aligned electrospun poly(l-lactide) nanofibers facilitate wound healing by inhibiting macrophage M1 polarization via the JAK-STAT and NF-κB pathways
J Xie, X Wu, S Zheng, K Lin, J Su - Journal of nanobiotechnology, 2022 - Springer
Delayed wound healing remains a challenge, and macrophages play an important role in
the inflammatory process of wound healing. Morphological changes in macrophages can …
the inflammatory process of wound healing. Morphological changes in macrophages can …
Development of porous scaffolds based on the in situ synthesis of biphasic calcium phosphate in a gelatin-polyvinyl alcohol matrix for bone tissue engineering
A Hassouna, H Elgharbawy, R Morsy - Journal of Molecular Structure, 2023 - Elsevier
Abstract 3D porous scaffolds are the preferred scaffold for tissue engineering applications
that require good biocompatibility and mechanical properties. However, those scaffolds …
that require good biocompatibility and mechanical properties. However, those scaffolds …
3D printed poly (lactic acid)-based nanocomposite scaffolds with bioactive coatings for tissue engineering applications
In this work, the effect of two different types of bioactive coatings on the properties of 3D
printed poly (lactic acid)/montmorillonite (PLA/MMT) nanocomposite scaffolds was …
printed poly (lactic acid)/montmorillonite (PLA/MMT) nanocomposite scaffolds was …
Exploring the physicochemical, electroactive, and biodelivery properties of metal nanoparticles on peripheral nerve regeneration
Despite the advances in the regeneration/rehabilitation field of damaged tissues, the
functional recovery of peripheral nerves (PNs), especially in a long gap injury, is considered …
functional recovery of peripheral nerves (PNs), especially in a long gap injury, is considered …
Effects of surface patterning and topography on the cellular functions of tissue engineered scaffolds with special reference to 3D bioprinting
The extracellular matrix (ECM) of the tissue organ exhibits a topography from the nano to
micrometer range, and the design of scaffolds has been inspired by the host environment …
micrometer range, and the design of scaffolds has been inspired by the host environment …
Development of a polyacrylamide/chitosan composite hydrogel conduit containing synergistic cues of elasticity and topographies for promoting peripheral nerve …
F Liu, J Xu, A Liu, L Wu, D Wang, Q Han, T Zheng… - Biomaterials …, 2022 - pubs.rsc.org
Substrate elasticity and topographical guidance are crucial factors for regulating tissue
regeneration, but the synergistic effects of both cues on peripheral nerve regeneration are …
regeneration, but the synergistic effects of both cues on peripheral nerve regeneration are …
3D chitosan scaffolds support expansion of human neural stem cells in chemically defined condition
FC Chang, MM James, AM Qassab, Y Zhou, Y Ando… - Matter, 2023 - cell.com
The use of human neural stem cells (hNSCs) for clinical cell therapies is limited by the lack
of effective culture substrates to produce hNSCs. Animal-sourced substrates could result in …
of effective culture substrates to produce hNSCs. Animal-sourced substrates could result in …
Recent advances in enhances peripheral nerve orientation: the synergy of micro or nano patterns with therapeutic tactics
Several studies suggest that topographical patterns influence nerve cell fate. Efforts have
been made to improve nerve cell functionality through this approach, focusing on …
been made to improve nerve cell functionality through this approach, focusing on …