Depression is a mood disorder characterized by abnormal thoughts. The pathophysiology of
depression is related to the deficiency of serotonin (5HT), which is derived from tryptophan …

The RAS (renin-angiotensin system) is the part of the endocrine system that plays a prime
role in the control of essential hypertension. Since the discovery of brain RAS in the …

Stroke is a huge burden on our society and this is expected to grow in the future due to the
aging population and the associated co-morbidities. The improvement of acute stroke care …

Background Telmisartan, a potent angiotensin II type-1 receptor blocker as well as partial
PPAR–gamma agonist, has emerged as a versatile therapeutic agent with diverse …

Despite extensive research on epileptogenesis, there is still a need to investigate new
pathways and targeted therapeutic approaches in this complex process. Inflammation …

Telmisartan (TEL), a non-peptide blocker of the angiotensin II type 1 receptor, is a widely
used antihypertensive agent. Nevertheless, its neuronal ionic effects and how they …

The aim of this study was to investigate the possible beneficial role of telmisartan in cerebral
edema after traumatic brain injury (TBI) and the potential mechanisms related to the …

Abstract Purpose of Review This review examines the role of different viral infections in
epileptogenesis, with a focus on Herpesviruses such as Human Herpesvirus 6 (HHV-6) and …

Introduction: Despite the approval of a large number of antiepileptic agents over the past 25
years, there has been no significant improvement in efficacy of treatments, with one third of …

Background Poststroke epilepsy (PSE) is a common complication after ischemic stroke. This
study investigates the association between the use of angiotensin‐converting enzyme …