The recognition of microbial or danger-associated molecular patterns by complement
proteins initiates a cascade of events that culminates in the activation of surface complement …

Chronic inflammation increases the risk of several cancers, including gastric, colon, and
hepatic cancers. Conversely, tumors, similar to tissue injury, trigger an inflammatory …

In recent years, many paradigms concerning central nervous system (CNS) immunology
have been challenged and shifted, including the discovery of CNS-draining lymphatic …

The observation that a subset of cancer patients show evidence for spontaneous CD8+ T
cell priming against tumor-associated antigens has generated renewed interest in the innate …

Reactivation of cytotoxic CD8+ T-cell responses has set a new direction for cancer
immunotherapy. Neutralizing antibodies targeting immune checkpoint programmed cell …

Acanthamoeba is an opportunistic protozoa, which exists widely in nature and is mainly
distributed in soil and water. Acanthamoeba usually exists in two forms, trophozoites and …

Atherosclerosis is a chronic disease of the arterial wall where both innate and adaptive
immunoinflammatory mechanisms are involved. Inflammation is central at all stages of …

The complement system is an evolutionarily ancient key component of innate immunity
required for the detection and removal of invading pathogens. It was discovered more than …

Most higher animals require sight for survival, yet even minor distortions of the visual axis
can cause blindness. For this reason, intraocular inflammation is incompatible with good …

Background Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease in
which the risk of disease is influenced by complex genetic and environmental contributions …