Illuminating dendritic function with computational models
P Poirazi, A Papoutsi - Nature reviews neuroscience, 2020 - nature.com
Dendrites have always fascinated researchers: from the artistic drawings by Ramon y Cajal
to the beautiful recordings of today, neuroscientists have been striving to unravel the …
to the beautiful recordings of today, neuroscientists have been striving to unravel the …
Pyramidal neurons: dendritic structure and synaptic integration
N Spruston - Nature Reviews Neuroscience, 2008 - nature.com
Pyramidal neurons are characterized by their distinct apical and basal dendritic trees and
the pyramidal shape of their soma. They are found in several regions of the CNS and …
the pyramidal shape of their soma. They are found in several regions of the CNS and …
[HTML][HTML] Rate, timing, and cooperativity jointly determine cortical synaptic plasticity
Cortical long-term plasticity depends on firing rate, spike timing, and cooperativity among
inputs, but how these factors interact during realistic patterns of activity is unknown. Here we …
inputs, but how these factors interact during realistic patterns of activity is unknown. Here we …
NEURON: a tool for neuroscientists
ML Hines, NT Carnevale - The neuroscientist, 2001 - journals.sagepub.com
NEURON is a simulation environment for models of individual neurons and networks of
neurons that are closely linked to experimental data. NEURON provides tools for …
neurons that are closely linked to experimental data. NEURON provides tools for …
Dendritic excitability and synaptic plasticity
Most synaptic inputs are made onto the dendritic tree. Recent work has shown that dendrites
play an active role in transforming synaptic input into neuronal output and in defining the …
play an active role in transforming synaptic input into neuronal output and in defining the …
Interneuronal mechanisms of hippocampal theta oscillations in a full-scale model of the rodent CA1 circuit
The hippocampal theta rhythm plays important roles in information processing; however, the
mechanisms of its generation are not well understood. We developed a data-driven …
mechanisms of its generation are not well understood. We developed a data-driven …
Propagation of action potentials in dendrites depends on dendritic morphology
P Vetter, A Roth, M Häusser - Journal of neurophysiology, 2001 - journals.physiology.org
Action potential propagation links information processing in different regions of the dendritic
tree. To examine the contribution of dendritic morphology to the efficacy of propagation …
tree. To examine the contribution of dendritic morphology to the efficacy of propagation …
[HTML][HTML] Direct current stimulation boosts hebbian plasticity in vitro
Background There is evidence that transcranial direct current stimulation (tDCS) can
improve learning performance. Arguably, this effect is related to long term potentiation (LTP) …
improve learning performance. Arguably, this effect is related to long term potentiation (LTP) …
Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites
NP Poolos, M Migliore, D Johnston - Nature neuroscience, 2002 - nature.com
The dendrites of pyramidal neurons have markedly different electrical properties from those
of the soma, owing to the non-uniform distribution of voltage-gated ion channels in …
of the soma, owing to the non-uniform distribution of voltage-gated ion channels in …
Dendritic coincidence detection of EPSPs and action potentials
We describe a mechanism for coincidence detection mediated by the interaction between
backpropagating action potentials and EPSPs in neocortical pyramidal neurons. At distal …
backpropagating action potentials and EPSPs in neocortical pyramidal neurons. At distal …