Abstract Follistatin-like 1 (FSTL1) is a secreted glycoprotein displaying expression changes
during development and disease, among which cardiovascular disease, cancer, and …

Mucosal epithelium maintains tissue homeostasis through many processes, including
epithelial barrier function, which separates the environment from the tissue. The barrier …

Gasdermin B (GSDMB) on chromosome 17q21 demonstrates a strong genetic linkage to
asthma, but its function in asthma is unknown. Here we identified that GSDMB is highly …

Background We have previously shown that oncostatin M (OSM) levels are increased in
nasal polyps (NPs) of patients with chronic rhinosinusitis (CRS), as well as in …

Abstract Follistatin-like protein 1 (FSTL1) showed overexpression in the inflammatory
synovial pannus, serum, and synovial tissues of osteoarthritis (OA) patients. However …

Main forms of cellular signal transmission are known to be autocrine and paracrine
signaling. Several cells secrete messengers called autocrine or paracrine agents that can …

Liver diseases, including viral hepatitis, fatty liver, metabolic-associated fatty liver disease,
liver cirrhosis, alcoholic liver disease, and liver neoplasms, are major global health …

Rationale: The role of FSTL-1 (follistatin-like 1) in lung homeostasis is unknown. Objectives:
We aimed to define the impact of FSTL-1 attenuation on lung structure and function and to …

Background Cigarette smoke (CS) is a major risk factor for Chronic Obstructive Pulmonary
Disease (COPD). Follistatin-like protein 1 (FSTL1), a critical factor during embryogenesis …

Background Airway remodeling in patients with asthma, which leads to a decline in
pulmonary function, is likely the result of repeated exacerbations often provoked by …