In mammals, the first cell-fate decision occurs during preimplantation embryo development
when the inner cell mass (ICM) and trophectoderm (TE) lineages are established. The ICM …

Early mammal embryogenesis starts with oocyte fertilization, giving rise to the zygote. The
events that the newly formed zygote surpasses are crucial to the embryo developmental …

In brief Trophectoderm is the first tissue to differentiate in the early mammalian embryo and
is essential for hatching, implantation, and placentation. This review article discusses the …

Background In vitro production of hematopoietic stem/progenitor cells (HSPCs) from human-
induced pluripotent stem cells (hiPSCs) provides opportunities for fundamental research …

Cancer is a disease portrayed by the uncontrolled growth of irregular cells. Tankyrase, a
member of poly (ADP-ribose) polymerase family, mediates Wnt signal transduction and has …

The time required for successful blastocyst formation varies among multiple species. The
formation of a blastocyst is governed by numerous molecular cell signaling pathways, such …

The Hippo signaling pathway is an important regulator of lineage segregation
(trophectoderm and inner cell mass) during blastocyst formation in the mouse embryos …

Simple Summary A high incidence of early pregnancy failures exists in beef and dairy cows.
This review describes various problems which occur during early gestation that contribute to …

Significant events that determine oocyte competence occur during follicular growth and
oocyte maturation. The anti-Mullerian hormone, a positive predictor of fertility, has been …

This review describes in detail the morphological, cytoskeletal and gene expression events
leading to the gene regulatory network bifurcation point of trophoblast and inner cell mass …