A tale of two cell-fates: role of the Hippo signaling pathway and transcription factors in early lineage formation in mouse preimplantation embryos
C Karasek, M Ashry, CS Driscoll… - Molecular human …, 2020 - academic.oup.com
In mammals, the first cell-fate decision occurs during preimplantation embryo development
when the inner cell mass (ICM) and trophectoderm (TE) lineages are established. The ICM …
when the inner cell mass (ICM) and trophectoderm (TE) lineages are established. The ICM …
Cell differentiation events in pre-implantation mouse and bovine embryos
Early mammal embryogenesis starts with oocyte fertilization, giving rise to the zygote. The
events that the newly formed zygote surpasses are crucial to the embryo developmental …
events that the newly formed zygote surpasses are crucial to the embryo developmental …
Trophectoderm formation: regulation of morphogenesis and gene expressions by RHO, ROCK, cell polarity, and HIPPO signaling
VB Alarcon, Y Marikawa - Reproduction, 2022 - rep.bioscientifica.com
In brief Trophectoderm is the first tissue to differentiate in the early mammalian embryo and
is essential for hatching, implantation, and placentation. This review article discusses the …
is essential for hatching, implantation, and placentation. This review article discusses the …
Role of YAP in hematopoietic differentiation and erythroid lineage specification of human-induced pluripotent stem cells
C Laowtammathron, C Lorthongpanich… - Stem Cell Research & …, 2023 - Springer
Background In vitro production of hematopoietic stem/progenitor cells (HSPCs) from human-
induced pluripotent stem cells (hiPSCs) provides opportunities for fundamental research …
induced pluripotent stem cells (hiPSCs) provides opportunities for fundamental research …
Tankyrase inhibitors: emerging and promising therapeutics for cancer treatment
Cancer is a disease portrayed by the uncontrolled growth of irregular cells. Tankyrase, a
member of poly (ADP-ribose) polymerase family, mediates Wnt signal transduction and has …
member of poly (ADP-ribose) polymerase family, mediates Wnt signal transduction and has …
A comparative analysis of hippo signaling pathway components during murine and bovine early mammalian embryogenesis
The time required for successful blastocyst formation varies among multiple species. The
formation of a blastocyst is governed by numerous molecular cell signaling pathways, such …
formation of a blastocyst is governed by numerous molecular cell signaling pathways, such …
Differential regulation of Hippo signaling pathway components between 8‐cell and blastocyst stages of bovine preimplantation embryogenesis
The Hippo signaling pathway is an important regulator of lineage segregation
(trophectoderm and inner cell mass) during blastocyst formation in the mouse embryos …
(trophectoderm and inner cell mass) during blastocyst formation in the mouse embryos …
Developmental Hurdles That Can Compromise Pregnancy during the First Month of Gestation in Cattle
Simple Summary A high incidence of early pregnancy failures exists in beef and dairy cows.
This review describes various problems which occur during early gestation that contribute to …
This review describes various problems which occur during early gestation that contribute to …
SMAD signaling pathway is disrupted by BPA via the AMH receptor in bovine granulosa cells
RH Patel, VB Truong, R Sabry, JE Acosta… - Biology of …, 2023 - academic.oup.com
Significant events that determine oocyte competence occur during follicular growth and
oocyte maturation. The anti-Mullerian hormone, a positive predictor of fertility, has been …
oocyte maturation. The anti-Mullerian hormone, a positive predictor of fertility, has been …
The first lineage determination in mammals
PL Pfeffer - Developmental Biology, 2024 - Elsevier
This review describes in detail the morphological, cytoskeletal and gene expression events
leading to the gene regulatory network bifurcation point of trophoblast and inner cell mass …
leading to the gene regulatory network bifurcation point of trophoblast and inner cell mass …