Potential pitfalls of using fractional anisotropy, axial diffusivity, and radial diffusivity as biomarkers of cerebral white matter microstructure
Fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD) are commonly
used as MRI biomarkers of white matter microstructure in diffusion MRI studies of …
used as MRI biomarkers of white matter microstructure in diffusion MRI studies of …
Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis
Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …
which can be compared across CNS regions, patients, and centres. In patients with multiple …
Probing myelin content of the human brain with MRI: A review
Rapid and efficient transmission of electric signals among neurons of vertebrates is ensured
by myelin‐insulating sheaths surrounding axons. Human cognition, sensation, and motor …
by myelin‐insulating sheaths surrounding axons. Human cognition, sensation, and motor …
So you want to image myelin using MRI: an overview and practical guide for myelin water imaging
Myelin water imaging (MWI) is an MRI imaging biomarker for myelin. This method can
generate an in vivo whole‐brain myelin water fraction map in approximately 10 minutes. It …
generate an in vivo whole‐brain myelin water fraction map in approximately 10 minutes. It …
[HTML][HTML] Quantitative MRI in leukodystrophies
MD Stellingwerff, PJW Pouwels, SD Roosendaal… - NeuroImage: Clinical, 2023 - Elsevier
Leukodystrophies constitute a large and heterogeneous group of genetic diseases primarily
affecting the white matter of the central nervous system. Different disorders target different …
affecting the white matter of the central nervous system. Different disorders target different …
[HTML][HTML] Myelin water imaging data analysis in less than one minute
Purpose Based on a deep learning neural network (NN) algorithm, a super fast and easy to
implement data analysis method was proposed for myelin water imaging (MWI) to calculate …
implement data analysis method was proposed for myelin water imaging (MWI) to calculate …
Associations between findings from myelin water imaging and cognitive performance among individuals with multiple sclerosis
S Abel, I Vavasour, LE Lee, P Johnson… - JAMA network …, 2020 - jamanetwork.com
Importance Cognitive impairment is a debilitating symptom of multiple sclerosis (MS) that
affects up to 70% of patients. An improved understanding of the underlying pathology of MS …
affects up to 70% of patients. An improved understanding of the underlying pathology of MS …
Multi‐spin echo T2 relaxation imaging with compressed sensing (METRICS) for rapid myelin water imaging
Purpose Myelin water imaging (MWI) provides a valuable biomarker for myelin, but clinical
application has been restricted by long acquisition times. Accelerating the standard multi …
application has been restricted by long acquisition times. Accelerating the standard multi …
[HTML][HTML] From pathology to MRI and back: Clinically relevant biomarkers of multiple sclerosis lesions
Focal lesions in both white and gray matter are characteristic of multiple sclerosis (MS).
Histopathological studies have helped define the main underlying pathological processes …
Histopathological studies have helped define the main underlying pathological processes …
Myelin water atlas: a template for myelin distribution in the brain
ABSTRACT BACKGROUND AND PURPOSE Myelin water imaging (MWI) is a magnetic
resonance imaging technique that quantifies myelin in‐vivo. Although MWI has been …
resonance imaging technique that quantifies myelin in‐vivo. Although MWI has been …