Highlights•The three major electron transfer routes are reviewed: 1st, 2nd (mediated
electron transfer) and 3rd generation biosensors (direct electron transfer).•Enzymatic …

The CAZy auxiliary activity family 3 (AA3) comprises enzymes from the glucose-methanol-
choline (GMC) family of oxidoreductases, which assist the activity of other AA family …

We report the first three-dimensional structure of fungus-derived glucose dehydrogenase
using flavin adenine dinucleotide (FAD) as the cofactor. This is currently the most advanced …

Background The glucose–methanol–choline (GMC) superfamily is a large and functionally
diverse family of oxidoreductases that share a common structural fold. Fungal members of …

5-Hydroxymethylfurfural oxidase (HMFO) is a flavin-dependent enzyme that catalyzes the
oxidation of many aldehydes, primary alcohols, and thiols. The three-step conversion of 5 …

Flavoenzymes can mediate a large variety of oxidation reactions through the activation of
oxygen. However, the O2 activation chemistry of flavin enzymes is not yet fully exploited …

Enzymes in the glucose–methanol–choline (GMC) oxidoreductase superfamily catalyze the
oxidation of an alcohol moiety to the corresponding aldehyde. In this review, the current …

C-glycosides are natural products with important biological activities but are recalcitrant to
degradation. Glycoside 3-oxidases (G3Oxs) are recently identified bacterial flavo-oxidases …

Lignocellulosic biomass from agricultural crop residues and forest waste represents an
abundant renewable resource for bioenergy and future biofuel. The current bottleneck of …

The genomes of three representative Polyporales (Bjerkandera adusta, Phlebia brevispora
and a member of the Ganoderma lucidum complex) recently were sequenced to expand our …