Obesity and type 2 diabetes mellitus: connections in epidemiology, pathogenesis, and treatments

R Ruze, T Liu, X Zou, J Song, Y Chen, R Xu… - Frontiers in …, 2023 - frontiersin.org
The prevalence of obesity and diabetes mellitus (DM) has been consistently increasing
worldwide. Sharing powerful genetic and environmental features in their pathogenesis …

Obesity and cancer risk: Emerging biological mechanisms and perspectives

KI Avgerinos, N Spyrou, CS Mantzoros, M Dalamaga - Metabolism, 2019 - Elsevier
Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …

Effect of a plant-based, low-fat diet versus an animal-based, ketogenic diet on ad libitum energy intake

KD Hall, J Guo, AB Courville, J Boring, R Brychta… - Nature medicine, 2021 - nature.com
The carbohydrate–insulin model of obesity posits that high-carbohydrate diets lead to
excess insulin secretion, thereby promoting fat accumulation and increasing energy intake …

Dietary intake of total, animal, and plant proteins and risk of all cause, cardiovascular, and cancer mortality: systematic review and dose-response meta-analysis of …

S Naghshi, O Sadeghi, WC Willett, A Esmaillzadeh - Bmj, 2020 - bmj.com
Objective To examine and quantify the potential dose-response relation between intake of
total, animal, and plant protein and the risk of mortality from all causes, cardiovascular …

Maintenance of lost weight and long-term management of obesity

KD Hall, S Kahan - Medical Clinics, 2018 - medical.theclinics.com
Robert is a 47-year-old patient who initially weighed 120 kilograms. He lost 40 kilograms 3
years ago by carefully following your guidance to decrease his caloric intake to 1500 …

Popular dietary patterns: alignment with American Heart Association 2021 dietary guidance: a scientific statement from the American Heart Association

CD Gardner, MK Vadiveloo, KS Petersen… - Circulation, 2023 - Am Heart Assoc
The evolution of dietary guidelines from isolated nutrients to broader dietary pattern
recommendations results from growing knowledge of the synergy between nutrients and …

Dietary protein intake and human health

G Wu - Food & function, 2016 - pubs.rsc.org
A protein consists of amino acids (AA) linked by peptide bonds. Dietary protein is hydrolyzed
by proteases and peptidases to generate AA, dipeptides, and tripeptides in the lumen of the …

Association between plant and animal protein intake and overall and cause-specific mortality

J Huang, LM Liao, SJ Weinstein, R Sinha… - JAMA internal …, 2020 - jamanetwork.com
Importance Although emphasis has recently been placed on the importance of high-protein
diets to overall health, a comprehensive analysis of long-term cause-specific mortality in …

Obesity energetics: body weight regulation and the effects of diet composition

KD Hall, J Guo - Gastroenterology, 2017 - Elsevier
Weight changes are accompanied by imbalances between calorie intake and expenditure.
This fact is often misinterpreted to suggest that obesity is caused by gluttony and sloth and …

Contribution of macronutrients to obesity: implications for precision nutrition

R San-Cristobal, S Navas-Carretero… - Nature Reviews …, 2020 - nature.com
The specific metabolic contribution of consuming different energy-yielding macronutrients
(namely, carbohydrates, protein and lipids) to obesity is a matter of active debate. In this …