Worldwide estimates predict 2 billion people will be aged over 65 years by 2050. A major
current challenge is maintaining mobility and quality of life into old age. Impaired mobility is …

Mobility is the most studied and most relevant physical ability affecting quality of life with
strong prognostic value for disability and survival. Natural selection has built the “engine” of …

Background Methods that facilitate muscle quality measurement may improve the diagnosis
of sarcopenia. Current research has focused on the phase angle (PhA) obtained through …

The term 'life course epidemiology'was coined in 1997 with the publication of the first edition
of A Life Course Approach to Chronic Disease Epidemiology. 1 This book reviewed the pre …

Background The relation between socioeconomic position (SEP) and obesity measured by
body mass index (BMI), a measure of weight for height, has been extensively reviewed in …

Introduction Multiple systematic reviews have investigated the relation between
socioeconomic position (SEP) and body mass index (BMI) throughout the life course …

Objective To evaluate for the first time the longitudinal relationship between abdominal
obesity and the onset of frailty. Methods Study based on results from two population‐based …

Background Obesity and chronic low-grade inflammation have both been implicated in the
onset of physical fatigue. However, few studies have investigated the independence of these …

Purpose This pilot study investigated differences in lean tissue mass, muscle strength,
muscle quality (strength per unit of muscle mass; MQ), and functional performance in healthy …

Background Muscle weakness, which increases in prevalence with age, is a major public
health concern. Grip strength is commonly used to identify weakness and an improved …