Members of the GroEL/HSP60 protein family have been studied for many years because of
their critical roles as ATP-dependent molecular chaperones, so it might come as a surprise …

Like all organisms, plants require energy for growth. They achieve this by absorbing light
and fixing it into a usable, chemical form via photosynthesis. The resulting carbohydrate …

Proteomics is the large-scale study of the structure and function of proteins in complex
biological sample. Such an approach has the potential value to understand the complex …

Here we review recent advances in understanding the regulation of mRNA synthesis in
Saccharomyces cerevisiae. Many fundamental gene regulatory mechanisms have been …

Proteins are macromolecules, which perform a large variety of functions. Most of them have
only a single function, but an increasing number of proteins are being identified as …

Genome sequences are now available that enable us to determine the biological
components that make up a cell or an organism. The discipline of systems biology examines …

Although glycolysis is a biochemical pathway that evolved under ancient anaerobic
terrestrial conditions, recent studies have provided evidence that some glycolytic enzymes …

The execution of complex biological processes requires the precise interaction and
regulation of thousands of molecules. Systematic approaches to study large numbers of …

Protein-DNA interactions (PDIs) mediate a broad range of functions essential for cellular
differentiation, function, and survival. However, it is still a daunting task to comprehensively …

Metabolic enzymes rarely regulate informational processes like gene expression. Yeast
acetyl-CoA synthetases (Acs1p and 2p) are exceptional, as they are important not only for …