Abstract The 'Vascular Depression'hypothesis posits that cerebrovascular disease may
predispose, precipitate or perpetuate some geriatric depressive syndromes. This hypothesis …

BACKGROUND: Voxel-based morphometry (VBM) has been widely used to quantify
structural brain changes associated with Major Depressive Disorder (MDD). While some …

In elderly people, depression mainly affects those with chronic medical illnesses and
cognitive impairment, causes suffering, family disruption, and disability, worsens the …

BACKGROUND: We aimed to review published work for the efficacy and safety of
electroconvulsive therapy (ECT) with simulated ECT, ECT versus pharmacotherapy, and …

BackgroundWhile depression is known to involve a disturbance of mood, movement and
cognition, its associated cognitive deficits are frequently viewed as simple epiphenomena of …

Objective: This study was a 20-year follow-up of offspring of depressed and nondepressed
parents to determine the magnitude and continuity of the risk of parental depression to the …

Diagnosis in psychiatry increasingly struggles to fulfil its key purposes, namely, to guide
treatment and to predict outcome. The clinical staging model, widely used in clinical …

Objective: The authors summarize current knowledge regarding the psychomotor symptoms
of depression. Method: Findings from the objective quantification of psychomotor symptoms …

There is a strong association between late-life depression, cognitive impairment,
cerebrovascular disease, and poor cognitive outcomes, including progressive dementia …

Psychomotor retardation is a long established component of depression that can have
significant clinical and therapeutic implications for treatment. Due to its negative impact on …