The essential physiological role of platelets in wound healing and tissue repair builds the
rationale for the use of human platelet derivatives in regenerative medicine. Abundant …

Mesenchymal stromal cells (MSC) emerged as highly attractive in cell-based regenerative
medicine. Initially thought to provide cells capable of differentiation towards mesenchymal …

The supplementation of culture medium with fetal bovine serum (FBS, also referred to as
“fetal calf serum”) is still common practice in cell culture applications. Due to a number of …

Most clinical applications of human multipotent mesenchymal stromal cells (MSCs) for cell
therapy, tissue engineering, regenerative medicine, and treatment of immune and …

A pathogen-free and standardized xeno-free supplement of growth media is required for the
ex vivo propagation of human cells used as advanced therapeutic medicinal products and …

Background aims Mesenchymal stromal cells (MSC) are ideal candidates for regenerative
and immunomodulatory therapies. The use of xenogeneic protein–free Good Manufacturing …

Purpose To investigate the cytokine composition and anti‐inflammatory effects of allogeneic
serum preparations for improved use as serum eye drops. Methods Serum of 15 healthy …

Human platelet lysate (PL) produced under optimal conditions of standardization and safety
has been increasingly suggested as the future 'gold standard'supplement to replace fetal …

A traditional concept in transfusion medicine is the expiration of platelet concentrates 5–7
days after collection due to storage conditions that favor the risks of bacterial contamination …

Serum is regarded as an essential supplement to promote survival and growth of cells
during culture. However, the potential risk of transmitting diseases disqualifies the use of …