Evidence for absence of links between striatal dopamine synthesis capacity and working memory capacity, spontaneous eye-blink rate, and trait impulsivity

R van den Bosch, FH Hezemans, JI Määttä, L Hofmans… - Elife, 2023 - elifesciences.org
Individual differences in striatal dopamine synthesis capacity have been associated with
working memory capacity, trait impulsivity, and spontaneous eye-blink rate (sEBR), as …

[HTML][HTML] On the role of behavioural modes during temporally extended decision-making and their neural substrates

N Kolling, J Scholl - Current Opinion in Behavioral Sciences, 2024 - Elsevier
Highlights●New advances in computational modelling, experimental design and theory
allow us to increasingly tackle complex decision problems.●Real-world decision-making …

Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans

JW Kanen, Q Luo, MR Kandroodi… - Psychological …, 2023 - cambridge.org
BackgroundThe non-selective serotonin 2A (5-HT2A) receptor agonist lysergic acid
diethylamide (LSD) holds promise as a treatment for some psychiatric disorders …

Dopaminergic modulation of dynamic emotion perception

BA Schuster, S Sowden, AJ Rybicki… - Journal of …, 2022 - Soc Neuroscience
Emotion recognition abilities are fundamental to our everyday social interaction. A large
number of clinical populations show impairments in this domain, with emotion recognition …

Human Brain Project partnering projects meeting: status quo and outlook

A Lorents, ME Colin, IE Bjerke, S Nougaret… - eneuro, 2023 - eneuro.org
As the European Flagship Human Brain Project (HBP) ends in September 2023, a meeting
dedicated to the Partnering Projects (PPs), a collective of independent research groups that …

Dopamine increases risky choice while D2 blockade shortens decision time

ST Hirschbichler, JC Rothwell, SG Manohar - Experimental Brain …, 2022 - Springer
Dopamine is crucially involved in decision-making and overstimulation within dopaminergic
pathways can lead to impulsive behaviour, including a desire to take risks and reduced …

[HTML][HTML] Activity in the dorsomedial striatum underlies serial reversal learning performance under probabilistic uncertainty

MK Young, KA Conn, J Das, S Zou, S Alexander… - … Psychiatry Global Open …, 2023 - Elsevier
Background Corticostriatal circuits, particularly the dorsomedial striatum (DMS) and lateral
orbitofrontal cortex, are critical for navigating reversal learning under probabilistic …

Network pharmacology, molecular docking, and experimental validation to explore the potential mechanism of Long Mu Qing Xin mixture for the treatment of attention …

X Li, Z Xiao, W Pu, Z Jiang, S Wang… - Frontiers in …, 2023 - frontiersin.org
Background: Long Mu Qing Xin Mixture (LMQXM) has shown potentially positive effects in
alleviating attention deficit hyperactivity disorder (ADHD); however, the action mechanism is …

[HTML][HTML] Impaired flexible reward learning in ADHD patients is associated with blunted reinforcement sensitivity and neural signals in ventral striatum and parietal …

HC Aster, M Waltmann, A Busch, M Romanos… - NeuroImage: Clinical, 2024 - Elsevier
Reward-based learning and decision-making are prime candidates to understand symptoms
of attention deficit hyperactivity disorder (ADHD). However, only limited evidence is …

Ketamine produces no detectable long-term positive or negative effects on cognitive flexibility or reinforcement learning of male rats

AN Nist, SJ Walsh, TA Shahan - Psychopharmacology, 2024 - Springer
Rationale Patients with major depressive disorder (MDD) often experience abnormalities in
behavioral adaptation following environmental changes (ie, cognitive flexibility) and tend to …