Corneal stromal wound healing is a complex event that occurs to restore the transparency of
an injured cornea. It involves immediate apoptosis of keratocytes followed by their activation …

The growth and maintenance of nearly every tissue in the body is influenced by systemic
hormones during embryonic development through puberty and into adulthood. Of the~ 130 …

Salivary exosomes have demonstrated vast therapeutic and diagnostic potential in
numerous diseases. This study pioneers previously unexplored roles of SE in the context of …

Previously we found that inhibitor of differentiation 3 (Id3) gene, a transcriptional repressor,
efficiently inhibits corneal keratocyte differentiation to myofibroblasts in vitro. This study …

Alkali burns are one of the most common injuries used in corneal wound healing studies.
Investigators have used different conditions to produce corneal alkali injuries that have …

Purpose IL-2 promotes activation, clonal expansion, and deletion of T cells. IL-2 signals
through its heterotrimeric receptor (IL-2R) consisting of the CD25, CD122 and CD132 …

Purpose: This pilot study investigated the in vivo therapeutic potential and tolerability of a
multimodal ophthalmic formulation, topical eye drops (TED), for acute mustard gas …

Our earlier decorin (Dcn) gene overexpression studies found that the targeted Dcn gene
transfer into the cornea inhibited corneal angiogenesis in vivo using a rabbit model. In this …

This study investigated the interplay between transforming growth factor beta (TGF-β1/T1
and TGF-β3/T3), and sex hormone receptors using our 3D in vitro cornea stroma model …

Acrolein is a highly reactive volatile toxic chemical that injures the eyes and many organs. It
has been used in wars and terrorism for wounding masses on multiple occasions and is …