Since the industrial revolution, the rapid growth and development of global industries have
depended largely upon the utilization of coal-derived chemicals, and more recently, the …

Covering: 2000 up to 2018 The cytochromes P450 (P450s) are a superfamily of heme-
containing monooxygenases that perform diverse catalytic roles in many species, including …

The cytochromes P450 (P450s or CYPs) constitute a large heme enzyme superfamily,
members of which catalyze the oxidative transformation of a wide range of organic …

One approach to bringing enzymes together for multienzyme biocatalysis is genetic fusion.
This enables the production of multifunctional enzymes that can be used for whole‐cell …

Fusion proteins, understood as those created by joining two or more genes that originally
encoded independent proteins, have numerous applications in biotechnology, from …

Understanding the molecular basis for controlled H2O2 activation is of fundamental
importance for peroxide-driven catalysis by metalloenzymes. In addition to O2 activation in …

Cytochrome P450 heme-thiolate monooxygenases are exceptionally versatile enzymes
which insert an oxygen atom into the unreactive C–H bonds of organic molecules. They …

Cytochrome P450s (CYPs) are heme-thiolated enzymes that catalyze the oxidation of C
single bond H bonds in a regio and stereoselective manner. Activation of the non-activated …

The majority of cytochrome P450 enzymes (CYPs) predominantly operate as
monooxygenases, but recently a class of P450 enzymes was discovered, that can act as …

CYP152 peroxygenases catalyze decarboxylation and hydroxylation of fatty acids using
H2O2 as cofactor. To understand the molecular basis for the chemo‐and regioselectivity of …