Designing of a next generation multiepitope based vaccine (MEV) against SARS-COV-2: Immunoinformatics and in silico approaches
Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
coronavirus 2 (SARS-COV-2) is a significant threat to global health security. Till date, no …
coronavirus 2 (SARS-COV-2) is a significant threat to global health security. Till date, no …
Multiepitope-based subunit vaccine design and evaluation against respiratory syncytial virus using reverse vaccinology approach
Respiratory syncytial virus (RSV) is primarily associated with respiratory disorders globally.
Despite the availability of information, there is still no competitive vaccine available for RSV …
Despite the availability of information, there is still no competitive vaccine available for RSV …
Designing a multi-epitope subunit vaccine against VP1 major coat protein of JC polyomavirus
S Kanse, M Khandelwal, RK Pandey, M Khokhar… - Vaccines, 2023 - mdpi.com
The JC polyomavirus virus (JCPyV) affects more than 80% of the human population in their
early life stage. It mainly affects immunocompromised individuals where virus replication in …
early life stage. It mainly affects immunocompromised individuals where virus replication in …
Recent advances in the development of virus-like particle-based flavivirus vaccines
N Zhang, C Li, S Jiang, L Du - Vaccines, 2020 - mdpi.com
Flaviviruses include several medically important viruses, such as Zika virus (ZIKV), Dengue
virus (DENV), West Nile virus (WNV) and Japanese encephalitis virus (JEV). They have …
virus (DENV), West Nile virus (WNV) and Japanese encephalitis virus (JEV). They have …
ATP-sensitive inward rectifier potassium channels reveal functional linkage between salivary gland function and blood feeding in the mosquito, Aedes aegypti
Reducing saliva secretions into the vertebrate host reduces feeding efficacy by most
hematophagous arthropods. However, seminal studies suggested saliva is not a …
hematophagous arthropods. However, seminal studies suggested saliva is not a …
Immuno-informatics guided designing of a multi-epitope vaccine against Dengue and Zika
A Bhardwaj, R Sharma, A Grover - Journal of Biomolecular …, 2023 - Taylor & Francis
Dengue and zika are amongst the most prevalent mosquito-borne diseases caused by
closely related members Dengue virus (DENV) and Zika virus (ZIKV), respectively, of the …
closely related members Dengue virus (DENV) and Zika virus (ZIKV), respectively, of the …
The role of Aedes aegypti in inducing/aggravating IgE-mediated allergic airway disease: extensive computational studies for identification of allergenic proteins
Respiratory allergies have become a major public health concern and affect one-third of the
world's population. Several factors like environmental changes, industrialization, and …
world's population. Several factors like environmental changes, industrialization, and …
An immunoinformatic approach to universal therapeutic vaccine design against BK virus
V Kesherwani, S Tarang - Vaccine, 2019 - Elsevier
In kidney transplant recipients (KTRs) long-term immunosuppression leads to BK virus
(BKV) reactivation, with an increased incidence of BKV-associated pathologies and allograft …
(BKV) reactivation, with an increased incidence of BKV-associated pathologies and allograft …
Effects of Aedes aegypti salivary protein on duck Tembusu virus replication and transmission in salivary glands
C Sri-In, A Thontiravong, LC Bartholomay… - Acta Tropica, 2022 - Elsevier
Duck Tembusu virus (DTMUV) infection is an arthropod-borne viral disease that affects
many poultry species, including ducks, chickens, and geese. Aedes aegypti mosquito is an …
many poultry species, including ducks, chickens, and geese. Aedes aegypti mosquito is an …
Tsetse salivary glycoproteins are modified with paucimannosidic N-glycans, are recognised by C-type lectins and bind to trypanosomes
RP Kozak, K Mondragon-Shem… - PLoS neglected …, 2021 - journals.plos.org
African sleeping sickness is caused by Trypanosoma brucei, a parasite transmitted by the
bite of a tsetse fly. Trypanosome infection induces a severe transcriptional downregulation of …
bite of a tsetse fly. Trypanosome infection induces a severe transcriptional downregulation of …