Living cells are exquisitely tuned to sense and respond to changes in their environment.
Repurposing these systems to create engineered biosensors has seen growing interest in …

Through the implementation of designable genetic circuits, engineered probiotic
microorganisms could be used as noninvasive diagnostic tools for the gastrointestinal tract …

Current plastic production and consumption routes are unsustainable due to impact upon
climate change and pollution, and therefore reform across the entire value chain is required …

A universal biochemical signal for bacterial cell–cell communication could facilitate
programming dynamic responses in diverse bacterial consortia. However, the classical …

The gut microbiome is shaped early in life by dietary and lifestyle factors. Specific
compounds in the gut affect the growth of different bacterial species and the production of …

Short-chain fatty acids (SCFAs) are commonly found in the large intestine, but generally not
in the small intestine, and influence microbiome composition and host physiology. Thus …

Engineered microorganisms such as the probiotic strain Escherichia coli Nissle 1917 (EcN)
offer a strategy to sense and modulate the concentration of metabolites or therapeutics in the …

The gut microbiome is increasingly understood to play a key role in human health.
Commensal gut microbes influence immunity, pathogen colonization, digestion, and brain …