Structure–activity relationships of 8-hydroxyquinoline-derived Mannich bases with tertiary amines targeting multidrug-resistant cancer

VFS Pape, R Palkó, S Tóth, MJ Szabó… - Journal of Medicinal …, 2022 - ACS Publications
A recently proposed strategy to overcome multidrug resistance (MDR) in cancer is to target
the collateral sensitivity of otherwise resistant cells. We designed a library of 120 …

Phosphate mediated biomimetic synthesis of tetrahydroisoquinoline alkaloids

T Pesnot, MC Gershater, JM Ward… - Chemical …, 2011 - pubs.rsc.org
Phosphate mediated biomimetic synthesis of tetrahydroisoquinoline alkaloids - Chemical
Communications (RSC Publishing) DOI:10.1039/C0CC05282E Royal Society of Chemistry …

Synthesis, characterisation and antimicrobial activity of new palladium and nickel complexes containing Schiff bases

CE Satheesh, PR Kumar, P Sharma, K Lingaraju… - Inorganica Chimica …, 2016 - Elsevier
New Schiff base ligands were synthesized by condensation of 2-(3, 4-dimethoxyphenyl)
ethanamine with 2-hydroxy benzaldehyde (L 1 H) and 2′-hydroxy acetophenone (L 2 H) …

Dopamine-based polyisoquinoline derivative: facile preparation and dual applications in efficient iodine capture and Ag nanoparticles immobilization

Y Liu, W Shi, X Sun, Z Xie - Journal of Environmental Chemical …, 2023 - Elsevier
Apart from the traditional polydopamine (PDA), which produced by the self-polymerization of
dopamine (DA), there are scarce reports regarding the construction of functional polymer by …

Consecutive Ring Expansion and Contraction for the Synthesis of 1‐Aryl Tetrahydroisoquinolines and Tetrahydrobenzazepines from Readily Available Heterocyclic …

JE Hill, JV Matlock, Q Lefebvre, KG Cooper… - Angewandte …, 2018 - Wiley Online Library
Tetrahydroisoquinolines and tetrahydrobenzazepines were prepared by acid‐promoted ring
contraction of cyclic ureas, which were themselves formed by ring expansion of indolines …

Enzyme Tunnel Dynamics and Catalytic Mechanism of Norcoclaurine Synthase: Insights from a Combined LiGaMD and DFT Study

X Wang, H Liu, J Wang, L Chang, J Cai… - The Journal of …, 2024 - ACS Publications
This study conducts a systematic investigation into the catalytic mechanism of norcoclaurine
synthase (NCS), a key enzyme in the biosynthesis of tetrahydroisoquinolines (THIQs) with …

Efficient Synthesis of Isoquinoline and Its Derivatives: From Metal Сatalysts to Catalyst-free Processes in Water

Y Yu, M Guan, YH Zhao, W Xie, Z Zhou… - Russian Journal of General …, 2020 - Springer
Isoquinolines constitute an important class of natural alkaloids, that demonstrate a wide
range of biological activities. Therefore, development of new methods for efficient synthesis …

Recent asymmetric syntheses of tetrahydroisoquinolines using “named” and some other newer methods

AL Zein, G Valluru, PE Georghiou - Studies in Natural Products Chemistry, 2012 - Elsevier
Isoquinoline alkaloids are a large family of natural products which have a broad variety of
biological activities. Among the members of this class of compounds …

New ON Schiff bases and their homoleptic Zn, Ni, and Cu complexes-Synthesis, structural characterization and DNA binding studies

CE Satheesh, PM Krishna, PR Kumar… - Journal of Molecular …, 2022 - Elsevier
New Schiff base ligands (L 1 H, L 2 H and L 3 H) and their homoleptic Zn (II)(1, 2 and 3), Ni
(II)(4, 5 and 6), and Cu (II)(7, 8 and 9) complexes have been synthesized. The ligands were …

Isoquinoline synthesis by CH activation/annulation using vinyl acetate as an acetylene equivalent

NJ Webb, SA Raw, SP Marsden - Tetrahedron, 2018 - Elsevier
Isoquinoline synthesis by CH activation/annulation using vinyl acetate as an acetylene equivalent
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