Making sense of it all: bacterial chemotaxis

GH Wadhams, JP Armitage - Nature reviews Molecular cell biology, 2004 - nature.com
Bacteria must be able to respond to a changing environment, and one way to respond is to
move. The transduction of sensory signals alters the concentration of small phosphorylated …

Histidine kinases and response regulator proteins in two-component signaling systems

AH West, AM Stock - Trends in biochemical sciences, 2001 - cell.com
Phosphotransfer-mediated signaling pathways allow cells to sense and respond to
environmental stimuli. Autophosphorylating histidine protein kinases provide phosphoryl …

Mapping allosteric communications within individual proteins

J Wang, A Jain, LR McDonald, C Gambogi… - Nature …, 2020 - nature.com
Allostery in proteins influences various biological processes such as regulation of gene
transcription and activities of enzymes and cell signaling. Computational approaches for …

Allostery and cooperativity revisited

Q Cui, M Karplus - Protein science, 2008 - Wiley Online Library
Although phenomenlogical models that account for cooperativity in allosteric systems date
back to the early and mid‐60's (eg, the KNF and MWC models), there is resurgent interest in …

Structural basis for control by phosphorylation

LN Johnson, RJ Lewis - Chemical reviews, 2001 - ACS Publications
Posttranslational modification by phosphorylation is a ubiquitous regulatory mechanism in
both eukaryotes and prokaryotes. Intracellular phosphorylation by protein kinases, triggered …

Fluoride and organic weak acids as modulators of microbial physiology

RE Marquis, SA Clock… - FEMS microbiology …, 2003 - academic.oup.com
Fluoride is widely used as an anticaries agent in drinking water and a variety of other
vehicles. This use has resulted in major health benefits. However, there are still open …

Polar Flagellar Motility of theVibrionaceae

LL McCarter - Microbiology and Molecular Biology Reviews, 2001 - Am Soc Microbiol
Polar flagella of Vibrio species can rotate at speeds as high as 100,000 rpm and effectively
propel the bacteria in liquid as fast as 60 μm/s. The sodium motive force powers rotation of …

How signals are heard during bacterial chemotaxis: protein-protein interactions in sensory signal propagation

A Bren, M Eisenbach - Journal of bacteriology, 2000 - Am Soc Microbiol
Chemotaxis is a mechanism by which bacteria efficiently and rapidly respond to changes in
the chemical composition of their environment, approaching chemically favorable …

[HTML][HTML] The structural basis of allosteric regulation in proteins

RA Laskowski, F Gerick, JM Thornton - FEBS letters, 2009 - Elsevier
Allosteric regulation of protein function occurs when the regulatory trigger, such as the
binding of a small-molecule effector or inhibitor, takes place some distance from the …

Structural basis of response regulator function

R Gao, S Bouillet, AM Stock - Annual review of microbiology, 2019 - annualreviews.org
Response regulators function as the output components of two-component systems, which
couple the sensing of environmental stimuli to adaptive responses. Response regulators …