A limbic brain area, the amygdala plays a key role in emotional responses and affective
states and disorders such as learned fear, anxiety, and depression. The amygdala has also …

Neuropeptides play important modulatory roles throughout the nervous system, functioning
as direct effectors or as interacting partners with other neuropeptide and neurotransmitter …

Perception of threats is essential for survival. Previous findings suggest that parallel
pathways independently relay innate threat signals from different sensory modalities to …

The amygdala is a limbic brain region that plays a key role in emotional processing,
neuropsychiatric disorders, and the emotional‐affective dimension of pain. Preclinical and …

Pain has a strong emotional component and is defined by its unpleasantness. Chronic pain
represents a complex disorder with anxio-depressive symptoms and cognitive deficits …

Dysregulation of pain neurocircuitry and neurochemistry has been increasingly recognized
as playing a critical role in a diverse spectrum of diseases including migraine, fibromyalgia …

The amygdala is a structure of the temporal lobe thought to be involved in assigning
emotional significance to environmental information and triggering adapted physiological …

The amygdala, a small deep brain structure involved in behavioral processing through
interactions with other brain regions, has garnered increased attention in recent years in …

Chronic pain is a common neurological disease involving lasting, multifaceted
maladaptations ranging from gene modulation to synaptic dysfunction and emotional …

Pain is an essential protective mechanism meant to prevent tissue damages in organisms.
On the other hand, chronic or persistent pain caused, for example, by inflammation or nerve …