Bioactive compounds and pharmacological and food applications of Syzygium cumini–a review
The present review explores the nutritional, phytochemical and pharmacological potential as
well as diverse food usages of Syzygium cumini. S. cumini is a traditional medicinal plant …
well as diverse food usages of Syzygium cumini. S. cumini is a traditional medicinal plant …
Phytochemical Profile, Biological Properties, and Food Applications of the Medicinal Plant Syzygium cumini
Syzygium cumini, locally known as Jamun in Asia, is a fruit-bearing crop belonging to the
Myrtaceae family. This study aims to summarize the most recent literature related to botany …
Myrtaceae family. This study aims to summarize the most recent literature related to botany …
Discovery of tropifexor (LJN452), a highly potent non-bile acid FXR agonist for the treatment of cholestatic liver diseases and nonalcoholic steatohepatitis (NASH)
DC Tully, PV Rucker, D Chianelli, J Williams, A Vidal… - 2017 - ACS Publications
The farnesoid X receptor (FXR) is a nuclear receptor that acts as a master regulator of bile
acid metabolism and signaling. Activation of FXR inhibits bile acid synthesis and increases …
acid metabolism and signaling. Activation of FXR inhibits bile acid synthesis and increases …
Jamun (Syzygium cumini (L.) Skeels) Seed: A Review on Nutritional Profile, Functional Food Properties, Health-Promoting Applications, and Safety Aspects
Jamun (Syzygium cumini L. Skeels) is highly perishable with a very short shelf life, hence,
jamun fruit is either consumed fresh as soon as it is harvested or converted to value-added …
jamun fruit is either consumed fresh as soon as it is harvested or converted to value-added …
A dual modulator of farnesoid X receptor and soluble epoxide hydrolase to counter nonalcoholic steatohepatitis
J Schmidt, M Rotter, T Weiser, S Wittmann… - Journal of medicinal …, 2017 - ACS Publications
Nonalcoholic steatohepatitis arising from Western diet and lifestyle is characterized by
accumulation of fat in liver causing inflammation and fibrosis. It evolves as serious health …
accumulation of fat in liver causing inflammation and fibrosis. It evolves as serious health …
Jamun (Syzygium cumini (L.) Skeels) seed bioactives and its biological activities: A review
Abstract Jamun (Syzygium cumini Skeels) is a nutritious fruit and has historically been used
as both as an edible and a traditional medicine. The jamun seed is an inedible by-product of …
as both as an edible and a traditional medicine. The jamun seed is an inedible by-product of …
Deciphering the structural determinants critical in attaining the FXR partial agonism
A Kumari, L Mittal, M Srivastava… - The Journal of …, 2023 - ACS Publications
Elucidation of structural determinants is pivotal for structure-based drug discovery. The
Farnesoid X receptor (FXR) is a proven target for NASH; however, its full agonism causes …
Farnesoid X receptor (FXR) is a proven target for NASH; however, its full agonism causes …
The role of bile acids in the human body and in the development of diseases
Y Shulpekova, M Zharkova, P Tkachenko, I Tikhonov… - Molecules, 2022 - mdpi.com
Bile acids are specific and quantitatively important organic components of bile, which are
synthesized by hepatocytes from cholesterol and are involved in the osmotic process that …
synthesized by hepatocytes from cholesterol and are involved in the osmotic process that …
Autophagy modulators in coronavirus diseases: a double strike in viral burden and inflammation
RCMC Silva, JS Ribeiro, GPD da Silva… - Frontiers in Cellular …, 2022 - frontiersin.org
Coronaviruses are the etiologic agents of several diseases. Coronaviruses of critical
medical importance are characterized by highly inflammatory pathophysiology, involving …
medical importance are characterized by highly inflammatory pathophysiology, involving …
Insights into the phenolic compounds present in jambolan (Syzygium cumini) along with their health‐promoting effects
Jambolan is a rich source of bioactive phenolic compounds that have many potential health
benefits. Phenolic acids, flavonoids (mainly anthocyanins, flavonols, flavanols and …
benefits. Phenolic acids, flavonoids (mainly anthocyanins, flavonols, flavanols and …