Stem cells can be defined as the cells that have the capacity to both self-renew and give rise
to differentiated cells. Under the right conditions and signals, depending on their origin and …

Cartilage injuries in children and adolescents are increasingly observed, with roughly 20%
of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) …

This book covers the latest research and advancements related to articular cartilage in
biology, development, pathology, clinical applications and tissue engineering. The authors …

Stem cell banks are increasingly recognized as an essential resource of biological materials
for both basic and translational stem cell research. By providing transnational access to …

Aims: Regenerative medicine is an emerging field with the potential to provide widespread
improvement in healthcare and patient wellbeing via the delivery of therapies that can …

Background: HP802-247 is a new-generation, allogeneic tissue engineering product
consisting of growth-arrested, human keratinocytes (K) and fibroblasts (F) delivered in a …

The need to better balance the promotion of scientific and technological innovation with risk
management for consumer protection has inspired several recent reforms attempting to …

Appropriate regulation of stem cell-based products is essential to ensure public safety and
trust while minimising unnecessary barriers to product development, but presents numerous …

Regulatory divergences and market fragmentation across member states have hampered
the development of the tissue engineering industry in the EU. Addressing this situation by …

Abstract The EU Regulation on Advanced Therapy Medicinal Products (ATMP) bridges a
regulatory gap and is expected to act as an enabler for the regenerative medicine sector in …